PDP1/PPAPDC2 Antibody - BSA Free

Western Blot: PDP1/PPAPDC2 Antibody [NBP1-76245] - Raji cell lysate with PDP1/PPAPDC2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

Immunocytochemistry/ Immunofluorescence: PDP1/PPAPDC2 Antibody - BSA Free [NBP1-76245] - Immunofluorescence of PDP1/PPAPDC2 in Raji cells with PDP1/PPAPDC2 antibody at 20 u/mL.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

PDP1/PPAPDC2 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus human PPAPDC2. The immunogen is located within amino acids 170 - 220 of PPAPDC2. Amino Acid Squence: LVRRRRPAHNNQMD
• Predicted Species: Bovine (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PLPP6
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/mL
  • Western Blot 1 ug/ml
• Control Peptide:

  PDP1/PPAPDC2 Peptide (NBP1-76245PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for PDP1/PPAPDC2 Antibody - BSA Free

• bA6J24.6
• EC 3.1.3
• EC 3.1.3.-
• FLJ46512
• FLJ90191
• MGC15483
• PDP1
• phosphatidic acid phosphatase type 2 domain containing 2
• Phosphatidic acid phosphatase type 2 domain-containing protein 2
• polyisoprenoid diphosphate phosphatase type 1
• PPAP2 domain-containing protein 2
• presqualene diphosphate phosphatase
• PSDP

Background

PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLPP6
• Uniprot:
  • NP_982278(Human)