PBR Antibody (2393B) [Alexa Fluor® 405]

• Reactivity: Hu, Mu
• Applications: WB, IHC, ICC/IF
• Clone: 2393B
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 405

PBR Antibody (2393B) [Alexa Fluor® 405] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Synthetic peptide containing human PBR
  Accession # P30536
• Specificity: Detects human PBR in direct ELISAs. Detects human and mouse PBR in Western blots.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PBR Antibody (2393B) [Alexa Fluor® 405]

• benzodiazepine peripheral binding site
• BZRPDBI
• IBP
• MBRPBS
• mDRC
• Mitochondrial benzodiazepine receptor
• PBR
• PBRBPBS
• PBRS
• peripheral benzodiazepine receptor
• Peripheral-type benzodiazepine receptor
• pk18
• PKBSbenzodiazapine receptor (peripheral)
• PTBR
• translocator protein (18kDa)
• translocator protein
• TSPO

Background

PBR promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism. PBR is expressed at the highest levels under normal conditions in tissues that synthesize steroids.  Aberrant expression of PBR has been linked to multiple diseases, including cancer, brain injury, neurodegeneration and ischemia-reperfusion injury.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.