PAUF/ZG16B Antibody (817310) [mFluor Violet 610 SE]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 817310
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

PAUF/ZG16B Antibody (817310) [mFluor Violet 610 SE] Summary

• Immunogen: E. coli-derived recombinant human PAUF/ZG16B
  Gly53-Arg208
  Accession # Q96DA0
• Specificity: Detects human PAUF/ZG16B in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ZG16B
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PAUF/ZG16B Antibody (817310) [mFluor Violet 610 SE]

• DKFZp762P2216
• EC 3.1.2
• EC 3.4.19.12
• EECP
• HRPE773
• hTrabid
• JCLN2
• LOC124220
• PAUF
• PRO1567
• TRABIDubiquitin thioesterase ZRANB1
• TRAF-binding protein domain
• ZG16B
• Zinc finger Ran-binding domain-containing protein 1
• zinc finger, RAN-binding domain containing 1

Background

PAUF (pancreatic adenocarcinoma upregulated factor), gene name ZG16B (zymogen granule protein 16B), is a 156 amino acid, approximately 20-25 kDa secreted protein that is a member of the jacalin-binding lectin family. PAUF expression is thought to be restricted to primates, but the related ZG16P, which shares approximately 25% amino acid sequence identity, is more widely expressed. Human PAUF is overexpressed in pancreatic adenocarcinoma, binds Toll-like receptors TLR2 and TLR4, and inhibits CXCR4-dependent, TLR2-mediated NF-kB activation. It facilitates tumor growth, adhesiveness, and production of pro-tumorigenic cytokines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ZG16B