PARD6A Antibody

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: LYOPH

PARD6A Antibody Summary

• Description: Novus Biologicals Rabbit PARD6A Antibody (NBP1-41128) is a polyclonal antibody validated for use in IHC and WB. Anti-PARD6A Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic peptide derived from Nter domain of human PAR6 protein
• Specificity: Antiserum reacts specifically with human 38 kDa protein
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PARD6A
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:100-1:1 000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Antiserum
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Lyophilized powder, reconstituted in distilled water.

Alternate Names for PARD6A Antibody

• PAR-6 alpha
• par-6 partitioning defective 6 homolog alpha (C. elegans)
• PAR-6
• PAR6A
• PAR6alpha
• PAR-6Apar-6 (partitioning defective 6, C.elegans) homolog alpha
• PAR6C
• partitioning defective 6 homolog alpha
• partitioning defective-6 homolog alpha
• partitioning-defective protein 6
• Tax interaction protein 40
• TAX40
• Tax-interacting protein 40
• TIP-40PAR6

Background

PAR6 is a cell membrane protein involved in cell polarization and asymmetrical cell division processes as part of a multi protein complex. It is thought to be involved in the invasive phenotype that is associated with metastatic carcinomas, playing a role in the epithelial to mesenchymal transition (EMT). PAR6 is also thought to be involved in the formation of epithelial tight junctions. PAR6 contains a semi Cdc42/Rac interactive binding (CRIB) domain and a PDZ (PSD95/Discs-large/ZO1) domain, and several different PAR6 isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PARD6A Antibody (NBP1-41128)(1)

Publication using NBP1-41128

• Campos Y, Qiu X, Gomero E et al. Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier. Nat Commun 2016-06-24 [PMID: 27336173] (WB, Mouse)

Bioinformatics

• Gene Symbol: PARD6A