Western Blot: BAF180/PB1 Antibody [NB100-79833] - Detection of Human and Mouse PB1/BAF180 by Western Blot. Samples : Whole cell lysate from HeLa (5, 15 and 50 ug), and 293T (50ug), and Mouse NIH3T3 (50ug) cells prepared ...read more
Immunohistochemistry: BAF180/PB1 Antibody [NB100-79833] - Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti- PB1/BAF180 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB. ...read more
Western Blot: BAF180/PB1 Antibody [NB100-79833] - Detection of Human and Mouse PB1/BAF180 on HeLa whole cell lysate using NB100-79833. PB1/BAF180 was immunoprecipitated by rabbit anti-PB1/BAF180 antibody NB100-79832.
Western Blot: BAF180/PB1 Antibody [NB100-79833] - Whole cell lysate of HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells.
Immunohistochemistry-Paraffin: BAF180/PB1 Antibody [NB100-79833] - Section of human prostate carcinoma.
The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. PB1/BAF180 is a component of the SWI/SNF-B (PBAF) complex. It contains six bromodomains which are defined by a 110 amino-acid module that interacts with acetylated lysine and is found in many chromatin binding proteins and histone acetyltransferases. PB1/BAF180 has been proposed to function as a tumor suppressor protein. Recently, PB1/BAF180 has been found to play a role in mediating cell cycle arrest in response to DNA damage via the regulation of the tumor suppressor p21. Alternate names for PB1/BAF180 include protein polybromo-1, polybromo-1D, BRG1-associated factor 180, hPB1, and PBRM1.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.