Pappalysin-1/PAPP-A Antibody (PAPP A1-24) - BSA Free



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Pappalysin-1/PAPP-A Antibody (PAPP A1-24) - BSA Free Summary

native human PAPP-A
The epitope is located on the PAPP-A subunit of the heterotetramer.
specific for native human PAPP-A. Heat and SDS denatured PAPP-A is also recognized, but not acid treated PAPP-A.
IgG1 Kappa
Protein A purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl
15mM Sodium Azide
1.0 mg/ml
Protein A purified

Reactivity Notes



Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Pappalysin-1/PAPP-A Antibody (NBP1-05043). (Showing 1 - 1 of 1 FAQ).

  1. I am highly interested to use couple of Anti-PAPP-A antibodies from your reputed companies for my research work. I have got the information regarding the immunogen used to generate these antibodies, however could not get any information regarding the specific amino acids/epitope to which your Anti-PAPP-A Antibodies binds with the antigen (PAPP-A).
    • Unfortunately, none of our PAPP A antibodies have been epitope mapped. Many of them have also been generated against full-length PAPP A, so there are many potential binding sites.

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Gene Symbol PAPPA

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