pan Cadherin Antibody

Images

 
Western Blot: pan Cadherin Antibody [H00000999-D01P] - Analysis of CDH1 expression in human pancreas.
Western Blot: pan Cadherin Antibody [H00000999-D01P] - Analysis of CDH1 expression in mouse lung.

Product Details

Summary
Reactivity Hu, Mu, HaSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

pan Cadherin Antibody Summary

Immunogen
CDH1 (ENSP00000261769, 1 a.a. - 882 a.a.) full-length human protein. MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD
Marker
Plasma Membrane Marker
Specificity
Reacts with cadherin 1, type 1, E-cadherin (epithelial).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CDH1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This antibody is reactive against transfected lysate and as a detection antibody in ELISA.
Reviewed Applications
Read 1 Review rated 5
using
H00000999-D01P in the following application:

Publications
Read Publications using
H00000999-D01P in the following applications:

  • WB
    1 publication

Reactivity Notes

Hamster reactivity reported in scientific literature (PMID: 24040379).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

Quality control test: Antibody reactive against mammalian tissue lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for pan Cadherin Antibody

  • Arc-1
  • Cadherin (pan)
  • cadherin 1, E-cadherin (epithelial)
  • cadherin 1, type 1, E-cadherin (epithelial)
  • cadherin-1
  • calcium-dependent adhesion protein, epithelial
  • CAM 120/80
  • CD324 antigen
  • CD324
  • CDHE
  • cell-CAM 120/80
  • ECAD
  • E-cadherin
  • Epithelial cadherin
  • LCAM
  • UVOE-Cadherin
  • uvomorulin

Background

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for pan Cadherin Antibody (H00000999-D01P)(3)

Review for pan Cadherin Antibody (H00000999-D01P) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Other.

Reviews using H00000999-D01P:
Filter by Applications
WB
(1)
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Filter by Species
Other
(1)
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Images Ratings Applications Species Date Details
Western Blot pan Cadherin H00000999-D01P
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reviewed by:
Anonymous
WB Other 03/28/2014
View

Summary

ApplicationWestern Blot
SpeciesOther

Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for pan Cadherin Antibody (H00000999-D01P). (Showing 1 - 1 of 1 FAQs).

  1. What concentration of anti-pan Cadherin Ab was used to for the Western blots shown above?
    • This product is an Abnova product and they typically dilute the Ab with a dilution range of 1:500-1:1000.

Secondary Antibodies

 

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Anonymous
03/28/2014
Application: WB
Species: Other

Bioinformatics

Gene Symbol CDH1
Entrez
Uniprot