PACS2 Antibody - BSA Free

Immunohistochemistry: PACS2 Antibody - BSA Free [NBP3-47233] - Immunohistochemistry of paraffin-embedded human liver tissue slide using ( PACS2 antibody) at dilution of 1:200

Western Blot: PACS2 Antibody - BSA Free [NBP3-47233] - Mouse brain tissue were subjected to SDS PAGE followed by western blot with (PACS2 antibody) at dilution of 1:600

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PACS2 Antibody - BSA Free Summary

• Immunogen: phosphofurin acidic cluster sorting protein 2. (Uniprot# Q86VP3)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PACS2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:10-1:100
  • Immunohistochemistry 1:50-1:500
  • Western Blot 1:500-1:1000
• Theoretical MW: 116 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for PACS2 Antibody - BSA Free

• FLJ25488
• KIAA0602phosphofurin acidic cluster sorting protein 1-like
• PACS1L
• PACS1-like protein
• PACS-2
• phosphofurin acidic cluster sorting protein 2

Background

Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PACS2