25 mM Tris-HCl, 1 mM EDTA, pH 7.5, 2 mM beta-mercaptoethanol, 1 mM dithiothreitol, 20% glycerol
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Recombinant Human p63/TP73L Protein
amplified in squamous cell carcinoma
Chronic ulcerative stomatitis protein
Keratinocyte transcription factor KET
p51tumor protein p53-like
Transformation-related protein 63
tumor protein 63
tumor protein p53-competing protein
tumor protein p63 deltaN isoform delta
tumor protein p63
Tumor protein p73-like
This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
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