p63/TP73L Antibody (TP63/1786)

Western Blot: p63/TP73L Antibody (TP63/1786) [NBP3-07441] - Western Blot Analysis MCF-7; T47D and MDA-MB453 cell lysate using p63/TP73L Mouse Monoclonal Antibody (TP63/1786).

Western Blot: p63/TP73L Antibody (TP63/1786) [NBP3-07441] - Western Blot of Recombinant, PC3 and HeLa cell lysates using p63/TP73L Mouse Monoclonal Antibody (TP63/1786).

Protein Array: p63/TP73L Antibody (TP63/1786) [NBP3-07441] - Analysis of Protein Array containing >19,000 full-length human proteins using p63/TP73L Mouse Monoclonal Antibody (TP63/1786).

• Reactivity: Hu
• Applications: WB, ELISA, MA
• Clone: TP63/1786
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

p63/TP73L Antibody (TP63/1786) Summary

• Description: 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08734)
  
  Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
• Immunogen: Recombinant fragment (around aa 3-106) of human p63/TP73L protein (exact sequence is proprietary) (Uniprot: Q9H3D4)
• Localization: Nuclear
• Marker: Squamous, Basal & Myoepithelial Cell Marker
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: TP63
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Protein Array
  • Western Blot 1-2 ug/ml
• Application Notes: ELISA: For coating, order Ab without BSA.
  Optimal dilution for a specific application should be determined.
• Theoretical MW: 63 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for p63/TP73L Antibody (TP63/1786)

• amplified in squamous cell carcinoma
• Chronic ulcerative stomatitis protein
• CUSP
• EEC3
• EEC3B(p51B)
• Keratinocyte transcription factor KET
• KET
• KETRHS
• LMS
• OFC8
• OFC8SHFM4TP73LNBP
• p40
• p51
• p51tumor protein p53-like
• p53CP
• p63
• p63AIS
• p73H
• p73L
• p73LB(p51A)
• SHFM4
• TP53CP
• TP53L
• TP63
• TP73L
• Transformation-related protein 63
• tumor protein 63
• tumor protein p53-competing protein
• tumor protein p63 deltaN isoform delta
• tumor protein p63
• Tumor protein p73-like

Background

The p63 gene, a homologue of the tumor suppressor p53, is highly expressed in the basal or progenitor layers of many epithelial tissues. P63 shows remarkable structural similarity to p53 and to the related p73 gene. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TP63
• Uniprot:
  • Q9H3D4()
  • Q9H3D4()