P2Y12/P2RY12 Antibody (HL2829)

P2Y12/P2RY12 antibody [HL2829] detects P2Y12/P2RY12 protein at cell membrane by immunofluorescent analysis.Sample: THP-1 cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: P2Y12/P2RY12 stained by P2Y12/P2RY12 antibody [HL2829] (NBP3-48736) diluted at 1:500.Blue: Fluoroshield with DAPI .

Unboiled Non-transfected (-) and transfected (+) 293T and Expi293 whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with P2Y12/P2RY12 antibody [HL2829] (NBP3-48736) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

• Reactivity: Hu
• Applications: ICC/IF
• Clone: HL2829
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

P2Y12/P2RY12 Antibody (HL2829) Summary

• Description: Novus Biologicals Rabbit P2Y12/P2RY12 Antibody (HL2829) (NBP3-48736) is a recombinant monoclonal antibody validated for use in ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Synthetic peptide encompassing a sequence within the Intracellular domain human of P2Y12/P2RY12. The exact sequence is proprietary.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: P2RY12
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for P2Y12/P2RY12 Antibody (HL2829)

• ADPG-R
• Gi-coupled ADP receptor HORK3
• HORK3
• HORK3P2Y12 platelet ADP receptor
• P2RY12
• P2T(AC)
• P2Y purinoceptor 12
• P2Y(AC)
• P2Y(ADP)
• P2Y(cyc)
• P2Y12
• P2Y12ADP-glucose receptor
• purinergic receptor P2RY12
• purinergic receptor P2Y, G-protein coupled, 12
• putative G-protein coupled receptor
• SP1999
• SP1999G-protein coupled receptor SP1999

Background

P2Y12 is a Purinergic Receptor essential for the aggregation of blood platelets. There is evidence that mutations in P2Y12 cause a bleeding disorder, suggesting that knowledge of the P2Y12 receptor could advance the development of antiplatelet agents to treat cardiovascular diseases. Expression of P2Y12 has been reported in platelets, spinal cord, and many brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries. Cognate

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: P2RY12