P2Y1/P2RY1 Antibody

Immunocytochemistry/Immunofluorescence: P2Y1/P2RY1 Antibody [NBP1-30741] - Dissociated rat hippocampal culture. Image courtesy of Janosch Heller, University College London.

• Reactivity: Hu, Mu, Rt, Gp
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: LYOPH

P2Y1/P2RY1 Antibody Summary

• Description: Novus Biologicals Rabbit P2Y1/P2RY1 Antibody (NBP1-30741) is a polyclonal antibody validated for use in IHC and ICC/IF. Anti-P2Y1/P2RY1 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A synthetic peptide from amino acid region 323-373 of mouse P2Y1/P2RY1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and human.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: P2RY1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:300-1:2000
  • Immunohistochemistry-Paraffin 1:300-1:2000
• Application Notes: P2Y1/P2RY1 antibody validated for ICC/IF from a verified customer review.

Reactivity Notes

Rat reactivity reported from a verified customer review.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the sample size is provided in reconstituted format.

Alternate Names for P2Y1/P2RY1 Antibody

• ATP receptor
• P2 purinoceptor subtype Y1
• P2RY1
• P2Y purinoceptor 1
• P2Y1
• P2Y1platelet ADP receptor
• purinergic receptor P2Y, G-protein coupled, 1
• Purinergic receptor

Background

P2Y1 is a Purinergic Receptor that causes a change in platelet shape and potentially leads to platelet aggregation by binding ADP, which results in the mobilization of intracellular calcium ions via activation of phospholipase C. This receptor also mediates the release of the relaxing factor nitric oxide and may be involved in the modulation of neuronal signal transmission. P2Y1 has been reported to be expressed in tissues throughout the body, particularly brain. ESTs have been isolated from human embryo, lung, and placenta libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for P2Y1/P2RY1 Antibody (NBP1-30741)(2)

Publications using NBP1-30741

• Zhao Y, Luo H, Ren X et Al. The P2Y(1) receptor in the colonic myenteric plexus of rats and its correlation with opioid-induced constipation BMC Gastroenterol 2024-01-08 [PMID: 38191294]
• Zhao Y, Ren X, Li F et al. P2Y1 receptor in the colonic submucosa of rats and its association with opioid induced constipation Experimental and Therapeutic Medicine 2022-12-13 [PMID: 36605532] (IF/IHC, Rat)

Review for P2Y1/P2RY1 Antibody (NBP1-30741) (1)

Average Rating: 4

(Based on 1 review)

We have 1 review tested in 1 species: Rat.

reviewed by: Bryan Tinsley ICC Rat 08/27/2014

Summary

• Application: Immunocytochemistry
• Species: Rat

Bioinformatics

• Gene Symbol: P2RY1
• Entrez:
  • 5028(Human)
  • 18441(Mouse)
  • 25265(Rat)
• Uniprot:
  • P49650(Mouse)