Perilipin-3/TIP47 Antibody


Western Blot: TIP47 Antibody [NB110-40764] - Detection of TIP47 in 3T3 L1 lysate.
Immunocytochemistry/ Immunofluorescence: TIP47 Antibody [NB110-40764] - TIP47 antibody was tested in U2OS cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 549 more

Product Details

Reactivity Hu, Mu, Po, PmSpecies Glossary
Applications WB, ICC/IF
1.00 mg/ml

Perilipin-3/TIP47 Antibody Summary

A synthetic peptide made to a region within the C-terminus (within residues 350-435) of the human TIP47 protein. [Swiss-Prot# O60664]
Cytoplasm. Endosome. Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails.
Immunogen affinity purified
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Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Tris-glycine, 150 mM NaCl
0.05% Sodium Azide
1.00 mg/ml
Immunogen affinity purified


  • Western Blot 2 ug/ml
  • Immunocytochemistry/Immunofluorescence 1:100
Application Notes
This TIP47 antibody is useful for Western Blot and Immunocytochemistry/Immunofluorescence. In Western Blot analysis, a band is seen at ~47 kDa, representing isoform B in both human (faint) and mouse lysates. In some samples, a ~28 kDa band may be observed which represents a splice isoform. In ICC/IF, endosomal staining was observed in U2OS cells.
Control Peptide
Perilipin-3/TIP47 Peptide (NB110-40764PEP)
Read Publications using
NB110-40764 in the following applications:

Reactivity Notes

Human, mouse, primate and porcine.

Alternate Names for Perilipin-3/TIP47 Antibody

  • Cargo selection protein TIP47
  • M6PRBP1
  • M6PRBP1MGC2012
  • Mannose-6-phosphate receptor-binding protein 1
  • perilipin 3,47 kDa MPR-binding protein
  • Perilipin3
  • perilipin-3
  • Placental protein 17,47 kDa mannose 6-phosphate receptor-binding protein
  • PLIN3
  • PP17
  • PP17MGC11117
  • tail-interacting protein, 47 kD
  • TIP47
  • TIP47mannose-6-phosphate receptor binding protein 1


TIP47 (tail-interacting protein 47) is a member of PAT family of proteins (perilipin, ADRP, S3-12 and OXPAT) which plays a key role in the packaging/storage of neutral lipids and is required for mannose 6-phosphate receptors (M6PR) transport from endosomes to trans-Golgi network (TGN). TIP47 localizes in cytoplasm, endosome membrane as peripheral membrane protein towards cytoplasmic side, core of lipid bodies/ lipid droplet, in lipid sails and in the envelope, and it interacts with M6PR, IGF2R etc. via the cytoplasmic domain. As a cargo protein, TIP47 facilitates the delivery of M6PR from endosomes to TGN where it binds to cytoplasmic domains of cation-independent/-dependent M6PR and translocates to late endosomes by binding to Rab9 GTPase. Like other PAT family members, TIP47 associates with lipid droplets and influence insulin signaling as evidenced by combined knockout of ADRPTIP47 leading to decreased insulin sensitivity. During HIV-1 infection, TIP47 acts as a cellular cofactor playing a part in Env incorporation, allowing the encounter and physical association between HIV-1 Gag and Env proteins during viral assembly process. TIP47 is identical to pregnancy-related placental tissue protein 17b (PP17b) and is overexpressed in cervical carcinoma patients wherein it is considered a serum tumor marker.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Perilipin-3/TIP47 Antibody (NB110-40764)(4)

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Product General Protocols

View specific protocols for Perilipin-3/TIP47 Antibody (NB110-40764): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Perilipin-3/TIP47 Antibody (NB110-40764) (0)

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NB110-40764AF405
Alexa Fluor (R) 488 Labeled NB110-40764AF488
Alexa Fluor (R) 647 Labeled NB110-40764AF647
Alexa Fluor (R) 700 Labeled NB110-40764AF700
Biotin Labeled NB110-40764B
DyLight 405 Labeled NB110-40764V
DyLight 488 Labeled NB110-40764G
DyLight 550 Labeled NB110-40764R
DyLight 650 Labeled NB110-40764C
FITC Labeled NB110-40764F
HRP Labeled NB110-40764H

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Contact Information

Product PDFs


Gene Symbol PLIN3

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