Orc2 Antibody

Images

 
Western Blot: Orc2 Antibody [NBP1-33189] - Sample (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE ORC2 antibody, antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: Orc2 Antibody [NBP1-33189] - Paraffin-embedded CL1-0 Xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity Hu, BvSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.45 mg/ml

Order Details

Orc2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human ORC2. The exact sequence is proprietary.
Localization
Nucleus
Marker
Chromatin Marker
Predicted Species
Bovine (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ORC2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
66 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse (84%), Rat (84%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.45 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Orc2 Antibody

  • ORC2Lorigin recognition complex subunit 2
  • origin recognition complex protein 2 homolog
  • origin recognition complex, subunit 2 (yeast homolog)-like
  • origin recognition complex, subunit 2 homolog (yeast)
  • origin recognition complex, subunit 2 homolog
  • origin recognition complex, subunit 2
  • origin recognition complex, subunit 2-like (yeast)
  • origin recognition complex, subunit 2-like

Background

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3L, -4L, and -5L. It also interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ORC2