OPA1 Antibody [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Ch, Ze, Pm, ZeSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 549

OPA1 Antibody [Janelia Fluor® 549] Summary

Immunogen
A synthetic peptide made to an internal region within residues 500-600 of human OPA1. [Swiss-Prot: O60313]
Localization
Mitochondrion; mitochondrial inner membrane; single-pass membrane protein. Mitochondrion; mitochondrial intermembrane space.
Predicted Species
Zebrafish (94%), Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OPA1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Zebrafish reactivity reported in scientific literature (PMID: 23516612, 26365306).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for OPA1 Antibody [Janelia Fluor® 549]

  • BERHS
  • EC 3.6.5.5
  • FLJ12460
  • KIAA0567dynamin-like 120 kDa protein, mitochondrial
  • LargeG
  • lilr3
  • MGM1
  • mitochondrial dynamin-like GTPase
  • MTDPS14
  • NPG
  • NPGlargeG
  • NTG
  • NTGmitochondrial dynamin-like 120 kDa protein
  • OPA1
  • optic atrophy 1 (autosomal dominant)
  • Optic atrophy protein 1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for OPA1 Antibody (NB110-55290JF549) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NB110-55290AF350
Alexa Fluor 405 NB110-55290AF405
Alexa Fluor 488 NB110-55290AF488
Alexa Fluor 532 NB110-55290AF532
Alexa Fluor 594 NB110-55290AF594
Alexa Fluor 647 NB110-55290AF647
Alexa Fluor 700 NB110-55290AF700
Alexa Fluor 750 NB110-55290AF750
Biotin NB110-55290B
DyLight 350 NB110-55290UV
DyLight 405 NB110-55290V
DyLight 488 NB110-55290G
DyLight 550 NB110-55290R
DyLight 594 NB110-55290DL594
DyLight 650 NB110-55290C
DyLight 680 NB110-55290FR
DyLight 755 NB110-55290IR
FITC NB110-55290F
HRP NB110-55290H
Janelia Fluor 549 NB110-55290JF549
Janelia Fluor 646 NB110-55290JF646

Additional OPA1 Products

Array NB110-55290JF549

Bioinformatics Tool for OPA1 Antibody (NB110-55290JF549)

Discover related pathways, diseases and genes to OPA1 Antibody (NB110-55290JF549). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for OPA1 Antibody (NB110-55290JF549)

Discover more about diseases related to OPA1 Antibody (NB110-55290JF549).
 

Pathways for OPA1 Antibody (NB110-55290JF549)

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PTMs for OPA1 Antibody (NB110-55290JF549)

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Research Areas for OPA1 Antibody (NB110-55290JF549)

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Blogs on OPA1.

Losing memory: Toxicity from mutant APP and amyloid beta explain the hippocampal neuronal damage in Alzheimer's disease
By Jamshed Arslan Pharm.D. Alzheimer's disease (AD) is an irreversible brain disorder that destroys memory and thinking skills. The telltale signs of AD brains are extracellular deposits of amyloid beta (a polypepti...  Read full blog post.

BNIP3 - a regulator of mitochondrial autophagy and cell death
Bcl-2 nineteen-kilodalton interacting protein 3 (BNIP3) is a pro-apoptotic BH3-only protein. BNIP3 localizes to the mitochondrial membrane where it plays a key role in mitochondrial autophagy and cell death pathways. Similar to other Bcl-2 family m...  Read full blog post.

Understanding OPA1 and Mitochondrial Function
OPA1 belongs to the Dynamin large GTPase protein family. OPA1 exists as a single-pass membrane protein localized in the mitochondrial inner membrane and also as a soluble form in the mitochondrial intermembrane space. There, it is a key player in fusi...  Read full blog post.

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Bioinformatics

Gene Symbol OPA1