Olig1 Antibody

Immunocytochemistry/Immunofluorescence: OLIG1 Antibody [NBP2-21066] - White matter of adult rat spinal cord using anti-rabbit Cy3-conjugated secondary antibodies (red) and DAPI (blue) as a nuclear counterstain.

Product Discontinued

Olig1 Antibody Summary

• Immunogen: SARPDAKEEQQQQLRC
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: OLIG1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:100-1:600
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera with PBS
• Preservative: 0.05% Sodium Azide
• Purity: Unpurified

Alternate Names for Olig1 Antibody

• BHLHB6
• bHLHe21
• Class B basic helix-loop-helix protein 6
• Class E basic helix-loop-helix protein 21
• helix-loop-helix protein, class B, 6
• Olig1
• oligo1
• oligodendrocyte lineage transcription factor 1
• oligodendrocyte transcription factor 1
• oligodendrocyte-specific bHLH transcription factor 1

Background

Olig1 and Olig2, which have been implicated in oligodendrogenesis, are expressed in the region of the ventral ventricular zone of late embryonic spinal cord where oligodendrocyte progenitors appear. Olig3 is transiently expressed in different types of progenitors of embryonic central nervous system and then disappears in the course of development. In adult, expression of Olig3 is primarily detected in neural tissues. Olig1 is also strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OLIG1