Olig1 Antibody

Western Blot: Olig1 Antibody [H00116448-D01P] - Analysis of OLIG1 expression in rat brain.

Western Blot: Olig1 Antibody [H00116448-D01P] - Analysis of OLIG1 expression in Raw 264.7.

Western Blot: Olig1 Antibody [H00116448-D01P] - Analysis of OLIG1 expression in mouse spleen.

Western Blot: Olig1 Antibody [H00116448-D01P] - Analysis of OLIG1 expression in transfected 293T cell line by OLIG1 polyclonal antibody.Lane 1: OLIG1 transfected lysate(26.20 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Olig1 Antibody Summary

• Immunogen: OLIG1 (NP_620450.1, 1 a.a. - 255 a.a.) full-length human protein. MLRPQRPGDLQLGASLYELVGYRQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGAGGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: OLIG1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Functional

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Olig1 Antibody

• BHLHB6
• bHLHe21
• Class B basic helix-loop-helix protein 6
• Class E basic helix-loop-helix protein 21
• helix-loop-helix protein, class B, 6
• Olig1
• oligo1
• oligodendrocyte lineage transcription factor 1
• oligodendrocyte transcription factor 1
• oligodendrocyte-specific bHLH transcription factor 1

Background

Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OLIG1
• Uniprot:
  • NP_620450.1(Human)