Olfactory Marker Protein Antibody - Azide and BSA Free

Immunohistochemistry-Paraffin: Olfactory Marker Protein Antibody [NB110-74753] - IHC on rat olfactory using Rabbit antibody to rat & mouse OMP (Olfactory Marker Protein): IgG (NB110-74753) at a concentration of 20 ug/ml in paraffin embeded section. Glomeruli are intensely stained. H&E counter stained.

• Reactivity: Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

Olfactory Marker Protein Antibody - Azide and BSA Free Summary

• Immunogen: A synthetic peptide from rat Olfactory Marker Protein conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in mouse.
• Localization: Cytoplasmic
• Specificity: Highly specific for mature olfactory neurons (including axon and terminals).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: OMP
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5-10 ug/ml
  • Immunohistochemistry-Paraffin 5-10 ug/ml
  • Western Blot 5-10 ug/ml
• Application Notes: For IHC, Zamboni's or 4% PFA fixatives are recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Ammonium sulfate precipitation
• Reconstitution Instructions: Reconstitute 0.5 mg size in 0.5 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the 0.1 mg size is provided in reconstituted format.

Alternate Names for Olfactory Marker Protein Antibody - Azide and BSA Free

• olfactory marker protein
• Olfactory neuronal-specific protein

Background

Olfactory marker protein (OMP) is an abundant, 19-kDa, cytosolic protein that is almost exclusively expressed in mature, functioning, olfactory neurons but not in the neural precursor basal cells. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Its tissue-specific expression in the receptor cells together with the results of the mouse knockout studies show that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. FUNCTION: May act as a modulator of the olfactory signal-transduction cascade. SUBUNIT: Interacts with BEX1 and BEX2. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Uniquely associated with mature olfactory receptor neurons. SIMILARITY: Belongs to the olfactory marker protein family.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OMP
• Entrez:
  • 18378(Mouse)
  • 24612(Rat)
• Uniprot:
  • P08523(Rat)