Numb Antibody - BSA Free

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Western Blot: Numb Antibody [NBP3-30927] - Western blot using anti-Numb antibody (Cat. No. NBP3-30927) on human brain lysate (14ug/lane). Antibody was used with (lane 1) and without (lane 2) blocking peptide at 10ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

Numb Antibody - BSA Free Summary

Description
Novus Biologicals Rabbit Numb Antibody - BSA Free (NBP3-30927) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
Synthetic peptide derived from human Numb protein
Clonality
Polyclonal
Host
Rabbit
Gene
NUMB
Purity
Antigen Affinity-purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry : 10-15 ug/ml
  • Western Blot : 1:400
Application Notes
.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Phosphate buffered saline
Preservative
0.08% Sodium Azide
Purity
Antigen Affinity-purified

Alternate Names for Numb Antibody - BSA Free

  • h-Numb
  • mnb
  • m-numb
  • numb (Drosophila) homolog
  • numb homolog (Drosophila)
  • Numb
  • protein numb homolog
  • Protein S171
  • S171

Background

Numb is a transmembrane signaling receptor that is activated by the DSL family of ligands. Studies suggestthat mammalian Numb plays a role in progenitor cell fate in neurogenesis. Numb exerts its role on cell fate by antagonizing Notch signaling. The mammalian Numb gene undergoes alternative splicing to produce at least four functionally different Numb isoforms which regulate different processes. A loss of Numb expression has been demonstrated in breast cancer, non-small cell lung cancer and chronic myelogenous leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NUMB