Numb Antibody - BSA Free Summary
| Description |
Novus Biologicals Rabbit Numb Antibody - BSA Free (NBP3-30927) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee. |
| Immunogen |
Synthetic peptide derived from human Numb protein |
| Clonality |
Polyclonal |
| Host |
Rabbit |
| Gene |
NUMB |
| Purity |
Antigen Affinity-purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- Immunohistochemistry : 10-15 ug/ml
- Western Blot : 1:400
|
| Application Notes |
. |
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles. |
| Buffer |
Phosphate buffered saline |
| Preservative |
0.08% Sodium Azide |
| Purity |
Antigen Affinity-purified |
Alternate Names for Numb Antibody - BSA Free
Background
Numb is a transmembrane signaling receptor that is activated by the DSL family of ligands. Studies suggestthat mammalian Numb plays a role in progenitor cell fate in neurogenesis. Numb exerts its role on cell fate by antagonizing Notch signaling. The mammalian Numb gene undergoes alternative splicing to produce at least four functionally different Numb isoforms which regulate different processes. A loss of Numb expression has been demonstrated in breast cancer, non-small cell lung cancer and chronic myelogenous leukemia.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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