Numb Products

Antibodies
Numb Antibody
Numb Antibody
NB500-178
Species: Hu, Mu, Ch, Rat
Applications: WB, Simple Western, ICC/IF
Host: Rabbit Polyclonal
Numb Antibody
Numb Antibody
NBP2-27181
Species: Hu, Mu, Rt, Bv, Pm
Applications: WB, IHC-P
Host: Rabbit Polyclonal
Numb Antibody (4F3)
Numb Antibody (4F3)
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
Antibody Pairs
Numb Antibody Pair
Numb Antibody Pair
H00008650-AP11
Species: Hu
Applications: S-ELISA
Numb Antibody Pair
Numb Antibody Pair
H00008650-AP21
Species: Hu
Applications: S-ELISA
Lysates
Numb Overexpression Lysate (D ...
Numb Overexpression Lysate (Denatu...
H00008650-T01
Species: Hu
Applications: WB
Numb Overexpression Lysate (N ...
Numb Overexpression Lysate (Native)
NBP2-08847
Applications: WB
Numb Overexpression Lysate (N ...
Numb Overexpression Lysate (Native)
NBP2-08848
Applications: WB
Proteins
Numb Peptide
Numb Peptide
NB500-178PEP
Species: Mu
Numb Recombinant Protein
Numb Recombinant Protein
H00008650-P01
Species: Hu
Applications: WB, ELISA, PA
Numb Peptide
Numb Peptide
NBP1-76576PEP
Species: Hu
Applications: AC
RNAi
Numb RNAi
Numb RNAi
H00008650-R02
Species: Hu
Numb RNAi
Numb RNAi
H00008650-R04
Species: Hu
Numb RNAi
Numb RNAi
H00008650-R03
Species: Hu

Description

Numb is a transmembrane signaling receptor that is activated by the DSL family of ligands. Studies suggestthat mammalian Numb plays a role in progenitor cell fate in neurogenesis. Numb exerts its role on cell fate by antagonizing Notch signaling. The mammalian Numb gene undergoes alternative splicing to produce at least four functionally different Numb isoforms which regulate different processes. A loss of Numb expression has been demonstrated in breast cancer, non-small cell lung cancer and chronic myelogenous leukemia.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 8650
Alternate Names
  • Protein S171
  • protein numb homolog
  • numb (Drosophila) homolog
  • S171
  • h-Numb
  • numb homolog (Drosophila)

Research Areas for Numb

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Growth and Development
Neuronal Cell Markers
Neuroscience
Stem Cell Markers
Stem Cell Signaling Pathway

Bioinformatics Tool for Numb

Discover related pathways, diseases and genes to Numb. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.