NTB-A/SLAMF6/CD352 Antibody (13G3-19D)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, IP
Clone
13G3-19D
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.5 mg/ml

NTB-A/SLAMF6/CD352 Antibody (13G3-19D) Summary

Immunogen
The immunogen for this antibody was Ly108.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SLAMF6
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Flow Cytometry 1:10-1:1000
  • Immunoprecipitation 1:10-1:500
Application Notes
This 13G3-19D antibody has been tested by flow cytometric analysis of mouse splenocytes and thymocytes. This can be used at less than or equal to 0.5 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous, may contain carrier protein/stabilizer.
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for NTB-A/SLAMF6/CD352 Antibody (13G3-19D)

  • Activating NK receptor
  • CD352 antigen
  • CD352
  • KALIFLJ50657
  • Ly108
  • NK-T-B-antigen
  • NTBA receptor
  • NTBA
  • NTB-A
  • NTB-AMGC104953
  • NTBAT- and B-cell antigen
  • SF2000
  • SLAM family member 6
  • SLAMF6

Background

The 13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is also known as NTB-A (NK cell, T cell, B cell antigen), and is expressed on NK, T cells, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and expression of IFN-gamma, and contributes to the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. CD4+ T cells from Ly108 knock-out mice exhibit diminished ability to produce IL-4 and defective neutrophil functions. Staining has not revealed any strain differences between C57BL/6 and BALB/c mice. Other strains have not been tested.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-43344AF405
Alexa Fluor 488 Labeled NBP1-43344AF488
Alexa Fluor 647 Labeled NBP1-43344AF647
Alexa Fluor 700 Labeled NBP1-43344AF700
Allophycocyanin Labeled NBP1-43344APC
Biotin Labeled NBP1-43578
DyLight 350 Labeled NBP1-43344UV
DyLight 405 Labeled NBP1-43344V
DyLight 488 Labeled NBP1-43344G
DyLight 680 Labeled NBP1-43344FR
DyLight 755 Labeled NBP1-43344IR
PE Labeled NBP1-43344PE
PerCP Labeled NBP1-43344PCP

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Bioinformatics Tool for NTB-A/SLAMF6/CD352 Antibody (NBP1-43344)

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Diseases for NTB-A/SLAMF6/CD352 Antibody (NBP1-43344)

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Bioinformatics

Gene Symbol SLAMF6
Entrez