NT-4 Antibody (36526) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Clone: 36526
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 647

NT-4 Antibody (36526) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects human NT-4 in direct ELISAs and Western blots. In Western blots, this antibody shows less than 1% cross‑reactivity with recombinant human (rh) NT-3 and rhBDNF.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NT-4 Antibody (36526) [Alexa Fluor™ Plus 647]

• GLC10
• GLC1O
• neurotrophic factor 4
• neurotrophic factor 5
• neurotrophin 4
• neurotrophin 5 (neurotrophin 4/5)
• neurotrophin-4
• neurotrophin-5
• Neutrophic factor 4
• NT4
• NT-4
• NT-4/5
• NT-5
• NTF4
• NTF5
• NTF5NT5

Background

NT-4 was originally identified as a mammalian homolog of the Xenopus neurotrophin, NT-4. Along with NGF, BDNF, and NT-3, it is a member of the NGF family of neurotrophic factors that are required for the differentiation and survival of specific neuronal subpopulations in both the central and the peripheral nervous systems. NT-4 functions through interactions with the TrkB receptor tyrosine kinase. Because mammalian NT-4 is much more divergent from its amphibian functional counterpart (Xenopus NT-4) than other family members, it is sometimes designated NT-5 or NT-4/5.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.