Nse2 Antibody - BSA Free

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Immunoprecipitation:Nse2 AntibodyNBP3-30136] -Detection of human MMS21 by western blot of immunoprecipitates. Samples: Whole cell lysate (1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

Nse2 Antibody - BSA Free Summary

Immunogen
Between 125 and 175
Assay Type
[Assay Type]
Sample Volume
[Sample Volume]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NSMCE2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8
Preservative
0.09% Sodium Azide
Purity
Affinity purified

Alternate Names for Nse2 Antibody - BSA Free

  • C8orf36
  • E3 SUMO-protein ligase NSE2
  • EC 6.3.2
  • EC 6.3.2.-
  • FLJ32440
  • hMMS21
  • methyl methanesulfonate sensitivity gene 21
  • MMS21 homolog
  • MMS21chromosome 8 open reading frame 36
  • non-SMC element 2 homolog (MMS21, S. cerevisiae)
  • Non-SMC element 2 homolog
  • non-SMC element 2, MMS21 homolog (S. cerevisiae)
  • Non-structural maintenance of chromosomes element 2 homolog
  • NSE2

Background

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks byhomologous recombination. The complex may promote sister chromatid homologous recombination by recruiting theSMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteinssuch as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is requiredfor the prevention of DNA damage-induced apoptosis by facilitating DNA repair

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NSMCE2