SMC5 Antibody

Images

 
Western Blot: SMC5 Antibody [NB100-469] - Samples: Whole cell lysate (50 ug) from 293T, HeLa, Jurkat, TCMK-1 and NIH3T3 cells. Antibodies: Affinity purified rabbit anti-SMC5 antibody (lot 2) used for WB at 1 ug/ml. ...read more
Immunoprecipitation: SMC5 Antibody [NB100-469] - 293T whole cell lysate.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
   

Biological Strategies

     

SMC5 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 1050 and the C-terminus (residue 1101) of human Structural Maintenance of Chromosomes 5 using the numbering given in TrEMBL entry Q8IY18 (GeneID 23137).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SMC5
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:5000-1:25000
  • Immunocytochemistry/Immunofluorescence
  • Immunoprecipitation 5 to 10 ug/mg lysate
Application Notes
Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 28302748).
Publications
Read Publications using
NB100-469 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SMC5 Antibody

  • hSMC5
  • KIAA0594SMC5 structural maintenance of chromosomes 5-like 1 (yeast)
  • SMC protein 5
  • SMC-5
  • SMC5L1SMC5 structural maintenance of chromosomes 5-like 1
  • structural maintenance of chromosomes 5
  • structural maintenance of chromosomes protein 5

Background

SMC (Structural maintenance of chromosomes) proteins are members of multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. Two of these complexes, cohesin and condensin consist of a core complex of an SMC1 and SMC3 heterodimer or an SMC2 and SMC4 heterodimer, respectively. A third complex includes a heterodimer of SMC5 and SMC6 whose function is not fully understood but is proposed to be related to DNA repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SMC5 Antibody (NB100-469)(3)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SMC5 Antibody (NB100-469) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SMC5
Entrez
Uniprot