The immunogen recognized by this antibody maps to a region between residues 1050 and the C-terminus (residue 1101) of human Structural Maintenance of Chromosomes 5 using the numbering given in TrEMBL entry Q8IY18 (GeneID 23137).
Immunogen affinity purified
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KIAA0594SMC5 structural maintenance of chromosomes 5-like 1 (yeast)
SMC protein 5
SMC5L1SMC5 structural maintenance of chromosomes 5-like 1
structural maintenance of chromosomes 5
structural maintenance of chromosomes protein 5
SMC (Structural maintenance of chromosomes) proteins are members of multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. Two of these complexes, cohesin and condensin consist of a core complex of an SMC1 and SMC3 heterodimer or an SMC2 and SMC4 heterodimer, respectively. A third complex includes a heterodimer of SMC5 and SMC6 whose function is not fully understood but is proposed to be related to DNA repair.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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