NRIP Antibody

Images

 
Western Blot: NRIP Antibody [H00055827-B01P] - Analysis of IQWD1 expression in transfected 293T cell line by IQWD1 polyclonal antibody. Lane 1: IQWD1 transfected lysate(56.43 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: NRIP Antibody [H00055827-B01P] - Analysis of purified antibody to IQWD1 on HeLa cell. (antibody concentration 10 ug/ml)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

NRIP Antibody Summary

Immunogen
IQWD1 (AAH25262.1, 1 a.a. ~ 513 a.a) full-length human protein.
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
DCAF6
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
This antibody is useful for Western Blot, Immunofluorescence

Reactivity Notes

This product is reactive against Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NRIP Antibody

  • 1200006M05Rik
  • Androgen receptor complex-associated protein
  • ARCAP
  • DDB1 and CUL4 associated factor 6
  • DDB1- and CUL4-associated factor 6
  • FLJ23798
  • IQ motif and WD repeat-containing protein 1
  • IQ motif and WD repeats 1
  • IQWD1
  • MSTP055
  • NRIP
  • Nuclear receptor interaction protein
  • PC326

Background

WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies. Their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up-regulates their transcriptional activity, thereby functioning as a nuclear receptor co-activator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer, thus indicating a potential therapeutic intervention. Northern Blot analysis detects a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Diseases for NRIP Antibody (H00055827-B01P)

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Bioinformatics

Gene Symbol DCAF6
Uniprot