NRIP Antibody

Product Discontinued

NRIP Antibody Summary

• Immunogen: IQWD1 (AAH25262.1, 1 a.a. ~ 513 a.a) full-length human protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: DCAF6
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Immunofluorescence

Reactivity Notes

This product is reactive against Human.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NRIP Antibody

• 1200006M05Rik
• Androgen receptor complex-associated protein
• ARCAP
• DDB1 and CUL4 associated factor 6
• DDB1- and CUL4-associated factor 6
• FLJ23798
• IQ motif and WD repeat-containing protein 1
• IQ motif and WD repeats 1
• IQWD1
• MSTP055
• NRIP
• Nuclear receptor interaction protein
• PC326

Background

WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies. Their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up-regulates their transcriptional activity, thereby functioning as a nuclear receptor co-activator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer, thus indicating a potential therapeutic intervention. Northern Blot analysis detects a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DCAF6
• Uniprot:
  • AAH25262.1(Human)