NPY1R Antibody - BSA Free

Immunohistochemistry-Paraffin: NPY1R Antibody [NLS1065] - Anti-NPY1R antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: NPY1R Antibody [NLS1065] - Analysis of anti-NPY1R antibody with human brain.

Immunohistochemistry-Paraffin: NPY1R Antibody [NLS1065] - Analysis of anti-NPY1R antibody with human brain at 16 ug/ml.

• Reactivity: Hu, Mu, Rt, Po, Bt, Ca, Eq, Gp, Pm, Pm, Rb, Ha, Sh
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

NPY1R Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human NPY1R.
• Epitope: 3rd cytoplasmic domain
• Localization: Secreted
• Specificity: Human NPY1R. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NPY6R (61%).
• Predicted Species: Sheep (94%), Hamster (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NPY1R
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 16 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Bovine (89%), Xenopus (83%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for NPY1R Antibody - BSA Free

• neuropeptide Y receptor type 1
• neuropeptide Y receptor Y1
• NPY1R
• NPY1-R
• NPYR
• NPYY1

Background

NPY1R belongs to the Neuropeptide Receptor GPCR family. Neuropeptide Y exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. NPY1R is the receptor for subtype 1 of neuropeptide Y. It has been implicated in central physiologic and pharmacologic NPY-induced analgesia. NPY1R expression has been documented in brain, breast, colon, ganglion, heart, and vessel. ESTs have been isolated from brain, breast, heart, kidney, placenta, skeletal muscle, testis, and vessel libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for NPY1R Antibody (NLS1065)(1)

Publication using NLS1065

• Matyal R, Mahmood F, Robich M et al. Chronic type II diabetes mellitus leads to changes in neuropeptide Y receptor expression and distribution in human myocardial tissue. Eur J Pharmacol. 2011-08-31 [PMID: 21549702] (IHC-P, Human)
  
  Details:
  IHC (P): human atrial tissue (Figs 7-9).

Bioinformatics

• Gene Symbol: NPY1R
• Entrez:
  • 4886(Human)
• Uniprot:
  • P25929()