NOMO Antibody [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 350

NOMO Antibody [Alexa Fluor® 350] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human NOMO
  Ser32- Asp1155
  Accession # Q15155
• Specificity: Detects human NOMO in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NOMO Antibody [Alexa Fluor® 350]

• NOMO
• NOMO2
• PM5

Background

NOMO, also known as pM5, is a 130 kDa type I membrane protein with no recognizable functional motif. It is a binding partner of Nicalin, a nicastin-related protein. The Nicalin/NOMO complex is localized in the ER and functions as an antagonist for Nodal and Activin signaling. Three copies of the NOMO gene, encoding NOMO isoforms 1, 2 and 3 have been described. The extracellular domains (ECD) of the isoforms share 99% amino acid sequence homology. The ECD of human and mouse NOMO also share 94% amino acid sequence homology.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.