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NOMO Products


Description

NOMO, also known as pM5, is a 130 kDa type I membrane protein with no recognizable functional motif. It is a binding partner of Nicalin, a nicastin-related protein. The Nicalin/NOMO complex is localized in the ER and functions as an antagonist for Nodal and Activin signaling. Three copies of the NOMO gene, encoding NOMO isoforms 1, 2 and 3 have been described. The extracellular domains (ECD) of the isoforms share 99% amino acid sequence homology. The ECD of human and mouse NOMO also share 94% amino acid sequence homology.

Bioinformatics

Uniprot
Product By Gene ID 283820
Alternate Names
  • NOMO
  • NOMO2
  • PM5