NGFR/TNFRSF16/p75NTR Antibody (NGFR5) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity Hu, Bb, Fe, Ft, Mk, Rb, Mu(-), Rt(-)Species Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
NGFR5
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

NGFR/TNFRSF16/p75NTR Antibody (NGFR5) [Janelia Fluor® 646] Summary

Immunogen
NGFR from A875 melanoma cells
Localization
Cell surface and cytoplasmic
Marker
Soft Tissue Tumor Marker
Specificity
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
NGFR
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Alternate Names for NGFR/TNFRSF16/p75NTR Antibody (NGFR5) [Janelia Fluor® 646]

  • CD271 antigen
  • CD271
  • Gp80-LNGFR
  • member 16
  • nerve growth factor receptor
  • NGF R
  • NGF receptor
  • NGFR
  • p75 ICD
  • p75 NTR
  • TNFRSF16
  • TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16)
  • tumor necrosis factor receptor superfamily member 16

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47965AF350
Alexa Fluor 405 NBP2-47965AF405
Alexa Fluor 488 NBP2-47965AF488
Alexa Fluor 532 NBP2-47965AF532
Alexa Fluor 594 NBP2-47965AF594
Alexa Fluor 647 NBP2-47965AF647
Alexa Fluor 700 NBP2-47965AF700
Alexa Fluor 750 NBP2-47965AF750
Allophycocyanin NBP2-47965APC
Allophycocyanin/Cy7 NBP2-47965APCCY7
Biotin NBP2-47965B
DyLight 350 NBP2-47965UV
DyLight 405 NBP2-47965V
DyLight 488 NBP2-47965G
DyLight 550 NBP2-47965R
DyLight 594 NBP2-47965DL594
DyLight 650 NBP2-47965C
DyLight 680 NBP2-47965FR
DyLight 755 NBP2-47965IR
FITC NBP2-47965F
HRP NBP2-47965H
Janelia Fluor 549 NBP2-47965JF549
Janelia Fluor 646 NBP2-47965JF646
PE NBP2-47965PE
PE/Atto594 NBP2-47965PEATT594
PE/Cy5.5 NBP2-47965PECY55
PE/Cy7 NBP2-47965PECY7
PerCP NBP2-47965PCP

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Bioinformatics

Gene Symbol NGFR
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