NCOA2 Antibody

Product Discontinued

NCOA2 Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residues 600 and 650 of human Nuclear Receptor Coactivator 2 using the numbering given in entry NP_006531.1 (GeneID 10499).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NCOA2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:500-1:5000
• Control:

  NCOA2 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for NCOA2 Antibody

• bHLHe75
• bHLHe75MGC138808
• Class E basic helix-loop-helix protein 75
• EC 2.3.1.48
• GRIP1glucocorticoid receptor-interacting protein-1
• HTIF2
• KAT13C
• NCOA2
• NCoA-2SRC2
• nuclear receptor coactivator 2
• TIF2
• TIF2hTIF2
• Transcriptional intermediary factor 2

Background

Hong et al. (1997) identified a coactivator for a steroid hormone receptor, which they termed glucocorticoid receptor-interacting protein-1 (GRIP1). This is the same protein as NCOA2.The level of NCOA2 protein increases during myogenesis. Immunohistochemistry analysis demonstrated that NCOA2 function is required for expression of MYOG and CDKN1A (116899) and for myogenic differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NCOA2
• Entrez:
  • 10499(Human)
• Uniprot:
  • NP_006531.1(Human)