| Reactivity | HuSpecies Glossary |
| Applications | Flow, CyTOF-ready |
| Clone | 920631 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Janelia Fluor 549 |
| Description | This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label. For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available. |
| Immunogen | E.coli-derived recombinant human NLRP6/NALP6 Lys35-Arg193 Accession # P59044 |
| Specificity | Detects human NLRP6/NALP6 in direct ELISAs. |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | NLRP6 |
| Purity | Protein A or G purified from hybridoma culture supernatant |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Recommended applications are based on validated applications from the unconjugated base product MAB9145. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols. |
| Storage | Store at 4C in the dark. |
| Buffer | 50mM Sodium Borate |
| Preservative | 0.05% Sodium Azide |
| Purity | Protein A or G purified from hybridoma culture supernatant |
Secondary Antibodies |
Isotype Controls |
Research Areas for NALP6 Antibody (FAB9145I)Find related products by research area.
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Pyroptosis: Mechanisms mediating cell death and pro-inflammatory cytokine release By Victoria OsinskiPyroptosis is an inflammatory form of programmed cell death characterized by the release of pro-inflammatory cytokines IL-1 beta and IL-18.1,10 It is a process distinct from apoptosis and necrosis (T... Read full blog post. |
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NALP6 - plays a critical role in suppressing inflammation and tumorigenesis NALP6 belongs to the NLRP family of which function as innate sensors of endogenous and exogenous stress and damage-associated molecular patterns (DAMPs). NLRPs are vital components of the inflammasome which is the cytoplasmic multiprotein complex that... Read full blog post. |
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| Gene Symbol | NLRP6 |