NAIP Antibody (SR1227) - BSA Free

Western Blot: NAIP Antibody (SR1227) [NBP3-22296] - Western blot analysis using NBP3-22296 in Human fetal kidney lysate.

• Reactivity: Hu
• Applications: WB
• Clone: SR1227
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

NAIP Antibody (SR1227) - BSA Free Summary

• Description: Novus Biologicals Rabbit NAIP Antibody (SR1227) - BSA Free (NBP3-22296) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human NAIP (Uniprot #: Q13075)
• Specificity: Detects endogenous levels of total NAIP
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: NAIP
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000
• Theoretical MW: 160 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for NAIP Antibody (SR1227) - BSA Free

• baculoviral IAP repeat-containing 1
• BIRC1
• BIRC1baculoviral IAP repeat-containing protein 1
• FLJ18088
• FLJ42520
• FLJ58811
• NAIP
• Neuronal apoptosis inhibitory protein
• NLR family, apoptosis inhibitory protein
• NLR family, BIR domain containing 1
• NLRB1
• nucleotide-binding oligomerization domain, leucine rich repeat and BIR domaincontaining 1
• psi neuronal apoptosis inhibitory protein
• psiNAIP

Background

Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy. Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules. Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NAIP