NAIP Products

Antibodies
NAIP Antibody [Unconjugated]
NAIP Antibody [Unconjugated]
AF829
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
NAIP Antibody (541609) [Uncon ...
NAIP Antibody (541609) [Unconjugated]
MAB829
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
NAIP Antibody
NAIP Antibody
NBP1-77196
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
NAIP Overexpression Lysate (N ...
NAIP Overexpression Lysate (Native)
NBP2-07863
Proteins
NAIP Partial Recombinant Prot ...
NAIP Partial Recombinant Protein
H00004671-Q01
Species: Hu
Applications: WB, ELISA, PA
NAIP Recombinant Protein Anti ...
NAIP Recombinant Protein Antigen
NBP1-88596PEP
Species: Hu
Applications: AC
NAIP Peptide
NAIP Peptide
NBP1-77196PEP
Species: Hu
Applications: AC
RNAi
NAIP RNAi
NAIP RNAi
H00004671-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy. Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules. Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 4671
Alternate Names
  • FLJ42520
  • psiNAIP
  • FLJ18088
  • psi neuronal apoptosis inhibitory protein
  • Neuronal apoptosis inhibitory protein
  • nucleotide-binding oligomerization domain, leucine rich repeat and BIR domaincontaining 1
  • baculoviral IAP repeat-containing 1
  • NLR family, BIR domain containing 1
  • NLRB1
  • BIRC1baculoviral IAP repeat-containing protein 1
  • FLJ58811
  • NLR family, apoptosis inhibitory protein

Research Areas for NAIP

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer

PTMs for NAIP

Learn more about PTMs related to NAIP.

Cleavage
Ubiquitination
Phosphorylation
Methylation

Bioinformatics Tool for NAIP

Discover related pathways, diseases and genes to NAIP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related NAIP Blog Posts

Check out the latest blog posts on NAIP.
Survivin - an inhibitor of apoptosis protein
Survivin is an anti-apoptotic protein which is the smallest protein within a large family of proteins including X-linked IAP, c-IAP1 and 2, IAP-like protein-2, melanoma IAP, NAIP, and Livin. Survivin is responsible for a wide range of basic cellula...    Read more.
Survivin is thrivin'
The survivin anti-apoptotic protein is the smallest member of a large family of proteins such as X-linked IAP, c-IAP1 and 2, IAP-like protein-2, melanoma IAP, Livin, and NAIP. Survivin regulates basic physiological events such as the cell cycle, tumor...    Read more.
Read more NAIP related blogs.