NAIP Products

NAIP Antibody
NAIP Antibody
Species: Hu, Mu, Ec
Applications: WB, ELISA, ICC/IF, IM, IP, PAGE, ICC/IF
Host: Rabbit Polyclonal
NAIP Antibody [Unconjugated]
NAIP Antibody [Unconjugated]
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
NAIP Antibody (541609) [Uncon ...
NAIP Antibody (541609) [Unconjugated]
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
Human NAIP ELISA Kit (Colorim ...
Human NAIP ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
NAIP Recombinant Protein Anti ...
NAIP Recombinant Protein Antigen
Species: Hu
Applications: AC
NAIP Antibody Blocking Peptid ...
NAIP Antibody Blocking Peptide
Species: Hu
Applications: AC


Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy. Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules. Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported.


Uniprot Human
Product By Gene ID 4671
Alternate Names
  • FLJ42520
  • psiNAIP
  • FLJ18088
  • psi neuronal apoptosis inhibitory protein
  • Neuronal apoptosis inhibitory protein
  • nucleotide-binding oligomerization domain, leucine rich repeat and BIR domaincontaining 1
  • baculoviral IAP repeat-containing 1
  • NLR family, BIR domain containing 1
  • NLRB1
  • BIRC1baculoviral IAP repeat-containing protein 1
  • FLJ58811
  • NLR family, apoptosis inhibitory protein

Research Areas for NAIP

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Learn more about PTMs related to NAIP.


Bioinformatics Tool for NAIP

Discover related pathways, diseases and genes to NAIP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related NAIP Blog Posts

Check out the latest blog posts on NAIP.

    Read more.
The Ins and Outs of Survivin
By Rachel M.A. Linger, Ph.D.What is survivin?Survivin is a small (16.5 kDa) protein normally found in human fetal tissue. In contrast, survivin is typically undetectable in most normal adult tissues. Expression of...    Read more.
Survivin - an inhibitor of apoptosis protein
Survivin is an anti-apoptotic protein which is the smallest protein within a large family of proteins including X-linked IAP, c-IAP1 and 2, IAP-like protein-2, melanoma IAP, NAIP, and Livin. Survivin is responsible for a wide range of basic cellula...    Read more.
Survivin is thrivin'
The survivin anti-apoptotic protein is the smallest member of a large family of proteins such as X-linked IAP, c-IAP1 and 2, IAP-like protein-2, melanoma IAP, Livin, and NAIP. Survivin regulates basic physiological events such as the cell cycle, tumor...    Read more.
Read more NAIP related blogs.