Myomesin 2 Antibody

Immunocytochemistry/Immunofluorescence: Myomesin 2 Antibody [NBP1-87496] - Immunofluorescent staining of human cell line HEK 293 shows localization to mitochondria.

Immunohistochemistry-Paraffin: Myomesin 2 Antibody [NBP1-87496] - Staining in human heart muscle and prostate tissues using anti-MYOM2 antibody. Corresponding MYOM2 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: Myomesin 2 Antibody [NBP1-87496] - Staining of human heart muscle shows high expression.

Immunohistochemistry-Paraffin: Myomesin 2 Antibody [NBP1-87496] - Staining of human prostate shows low expression as expected.

• Reactivity: Hu
• Applications: ICC/IF, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

Myomesin 2 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: STQASSQKSLSQRSSSQRASSQTSLGGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGF
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MYOM2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  Myomesin 2 Protein (NBP1-87496PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Myomesin 2 Antibody

• 165 kDa connectin-associated protein
• 165 kDa titin-associated protein
• M-band protein
• M-protein
• myomesin (M-protein) 2 (165kD)
• myomesin (M-protein) 2, 165kDa
• Myomesin family member 2
• myomesin-2
• titin-associated protein, 165 kD
• TTNAP

Background

Myomesin-1 (190 kDa) and myomesin-2 (165 kDa) are components of the vertebrate myofibrillar M band and are associated with Titin, Myosin and Connectin. The myomesin proteins are responsible for the formation of a head structure on one end of the Titin string that connects the Z and M bands of the sarcomere. Myomesin-1 and -2 have unique N-terminal domains and are expressed mainly in skeletal muscle. The gene encoding human myomesin-1 maps to chromosome 18p11.31-p11.32.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MYOM2