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Western Blot: Myelin PLP Antibody [NB100-74503] - Proteins were extracted from control (Ctrl) and stretched (Stretch) 158N cells and western blot was performed for myelin protein PLP (26 kDa) following 20% of strain. ...read more
Western Blot: Myelin PLP Antibody [NB100-74503] - Figure 1 shows a Western blot of PLP in adult mouse brain samples using NB100-74503. Figure 2 shows an immunocytochemical staining of PLP in mouse brain thick section ...read more
Western Blot: Myelin PLP Antibody [NB100-74503] - Analysis of adult mouse brain samples.
Useful in IHC and WB. WB: Detects an approx. 26 - 29 kDa protein representing the proteolipid protein in adult mouse brain samples. Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID: 20594620).
Read Publications using NB100-74503 in the following applications:
Rat reactivity reported in scientific literature (PMID: 20594620).
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
0.05% Sodium Azide
Alternate Names for Myelin PLP Antibody
major myelin proteolipid protein
myelin proteolipid protein
proteolipid protein 1
spastic paraplegia 2, uncomplicated
Myelin proteins associated with the central nervous system (CNS) are thought to be unique to the CNS, and play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. The proteolipid protein (PLP) and the splice variant DM20 are the predominant myelin proteins in the CNS. PLP is also one of the most extensively studied myelin proteins because of the prevelance of PLP mutations amongst humans and animals. Such mutations can lead to abnormal myelin formation resulting in conditions such as X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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