Myelin PLP Antibody

Images

 
Western Blot: Myelin PLP Antibody [NB100-74503] - Analysis of adult mouse brain samples.
Western Blot: Myelin PLP Antibody [NB100-74503] - Figure 1 shows a Western blot of PLP in adult mouse brain samples using NB100-74503. Figure 2 shows an immunocytochemical staining of PLP in mouse brain thick section ...read more

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, ICC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Myelin PLP Antibody Summary

Immunogen
Synthetic peptide corresponding to residues C(109) G K G L S A T V T G G Q K G R G S R G(128) of PLP.
Localization
Membrane; Multi pass membrane protein.
Marker
Oligodendrocyte Marker
Specificity
PLP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PLP1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunocytochemistry 1:1000
Application Notes
Useful in IHC and WB. WB: Detects an approx. 26 - 29 kDa protein representing the proteolipid protein in adult mouse brain samples.
Publications
Read Publications using
NB100-74503 in the following applications:

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 20594620).

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.05% Sodium Azide
Purity
Unpurified

Alternate Names for Myelin PLP Antibody

  • DM-20
  • HLD1
  • Lipophilin
  • major myelin proteolipid protein
  • MMPL
  • Myelin PLP
  • myelin proteolipid protein
  • PLP
  • PLP/DM20
  • PLP1
  • PMD
  • proteolipid protein 1
  • spastic paraplegia 2, uncomplicated
  • SPG2

Background

Myelin proteins associated with the central nervous system (CNS) are thought to be unique to the CNS, and play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. The proteolipid protein (PLP) and the splice variant DM20 are the predominant myelin proteins in the CNS. PLP is also one of the most extensively studied myelin proteins because of the prevelance of PLP mutations amongst humans and animals. Such mutations can lead to abnormal myelin formation resulting in conditions such as X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB600-717
Species: Hu, Mu, Rt, Po, Bv, Ch, GP, Ma, Rb, Sh
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, RI
NBP1-22568
Species: Hu
Applications: IHC-P
NBP2-19928
Species: Hu
Applications: WB, IHC, IHC-P
H00004340-B01P
Species: Hu, Rt
Applications: WB
NBP2-46617
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
NB300-141
Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Fe, GP, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P
H00000875-M01
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF, IHC-P, IP, RNAi
NBP1-19371
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
NBP2-32887
Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, PAGE, IF
NB600-41532
Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NB100-1607
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-46376
Species: Hu
Applications: WB, IHC
NB100-74503
Species: Mu, Rt
Applications: WB, ICC

Publications for Myelin PLP Antibody (NB100-74503)(2)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 2 applications: ICC/IF, WB.


Filter By Application
ICC/IF
(1)
WB
(1)
All Applications
Filter By Species
Rat
(1)
All Species

Reviews for Myelin PLP Antibody (NB100-74503) (0)

There are no reviews for Myelin PLP Antibody (NB100-74503). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Myelin PLP Antibody (NB100-74503) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Myelin PLP Products

Bioinformatics Tool for Myelin PLP Antibody (NB100-74503)

Discover related pathways, diseases and genes to Myelin PLP Antibody (NB100-74503). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Myelin PLP Antibody (NB100-74503)

Discover more about diseases related to Myelin PLP Antibody (NB100-74503).
 

Pathways for Myelin PLP Antibody (NB100-74503)

View related products by pathway.

PTMs for Myelin PLP Antibody (NB100-74503)

Learn more about PTMs related to Myelin PLP Antibody (NB100-74503).
 

Research Areas for Myelin PLP Antibody (NB100-74503)

Find related products by research area.

Blogs on Myelin PLP

There are no specific blogs for Myelin PLP, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Myelin PLP Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol PLP1
Entrez