Western Blot: Myelin PLP Antibody [NB100-74503] - Analysis of adult mouse brain samples.
Western Blot: Myelin PLP Antibody [NB100-74503] - Figure 1 shows a Western blot of PLP in adult mouse brain samples using NB100-74503. Figure 2 shows an immunocytochemical staining of PLP in mouse brain thick section ...read more
Mu, RtSpecies Glossary
This product is unpurified. The exact concentration of antibody is not quantifiable.
Rat reactivity reported in scientific literature (PMID: 20594620)
Alternate Names for Myelin PLP Antibody
major myelin proteolipid protein
myelin proteolipid protein
proteolipid protein 1
spastic paraplegia 2, uncomplicated
Myelin proteins associated with the central nervous system (CNS) are thought to be unique to the CNS, and play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. The proteolipid protein (PLP) and the splice variant DM20 are the predominant myelin proteins in the CNS. PLP is also one of the most extensively studied myelin proteins because of the prevelance of PLP mutations amongst humans and animals. Such mutations can lead to abnormal myelin formation resulting in conditions such as X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.