Musculin Antibody

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Western Blot: Musculin Antibody [NB100-789] - Staining of Human Bone Marrow lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Musculin Antibody Summary

Immunogen
Peptide with sequence C-PLKSDWNSLDGIIR corresponding to C-Terminus according to AAC15071.1.
Epitope
PLKSDWNSLDGIIR
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
MSC
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1 - 3 ug/ml
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Approx. 25 kDa band observed in human bone marrow lysates (calculated MW of 23.6 kDa band according to AAC15071.1).
Publications
Read Publication using NB100-789.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris (pH 7.3), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Musculin Antibody

  • ABF1
  • ABF-1activated B-cell factor 1, homolog of mouse musculin
  • Activated B-cell factor 1
  • BHLHA22
  • bHLHa22activated B-cell factor-1
  • Class A basic helix-loop-helix protein 22
  • musculin (activated B-cell factor-1)
  • musculin
  • MYOR

Background

The predicted 218-amino acid protein contains a bHLH motif, a putative nuclear localization signal, a glycine-rich region, and a stretch of acidic residues. MSC is capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro, and forms heterodimers with E2A proteins in vivo. MSC contains a transcriptional repression domain and is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. MSC is a downstream target of the B-cell receptor signal transduction pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Musculin Antibody (NB100-789)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol MSC
Entrez
Uniprot
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