Musculin Products

Antibodies
Musculin Antibody
Musculin Antibody
NB100-92290
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Musculin Antibody
Musculin Antibody
NBP2-38977
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Musculin Antibody
Musculin Antibody
NB100-789
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
Musculin Overexpression Lysat ...
Musculin Overexpression Lysate (Na...
NBP2-10525
Applications: WB
Proteins
Musculin Partial Recombinant ...
Musculin Partial Recombinant Protein
H00009242-Q01
Species: Hu
Applications: WB, ELISA, PA
Musculin Recombinant Protein
Musculin Recombinant Protein
H00009242-P01
Species: Hu
Applications: WB, ELISA, PA
Musculin Partial Recombinant ...
Musculin Partial Recombinant Protein
H00009242-Q02
Species: Hu
Applications: WB, ELISA, PA
RNAi
Musculin RNAi
Musculin RNAi
H00009242-R01
Species: Hu

Description

Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins, known to play an important role in the regulation of muscle cell development, includes MyoD, myogenin and musculin (also designated MyoR). Members of this group of transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many musclespecific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to represses MyoD activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 9242
Alternate Names
  • musculin (activated B-cell factor-1)
  • Activated B-cell factor 1
  • ABF1
  • BHLHA22
  • Class A basic helix-loop-helix protein 22
  • bHLHa22activated B-cell factor-1
  • ABF-1activated B-cell factor 1, homolog of mouse musculin
  • MYOR
  • musculin

Bioinformatics Tool for Musculin

Discover related pathways, diseases and genes to Musculin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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