MUC5AC Antibody (45M1) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Ch, Fe, Pm, Rb, Bv(-)Species Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Clone
45M1
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

MUC5AC Antibody (45M1) [DyLight 488] Summary

Immunogen
M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
Localization
Cytoplasmic
Specificity
This MAb recognizes the peptide core of gastric mucin M1 (>1,000 kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MUC5AC
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Hedgehog Porcine reactivity reported in scientific literature (PMID:33026343).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MUC5AC Antibody (45M1) [DyLight 488]

  • gastric mucin
  • leB
  • lewis B blood group antigen
  • major airway glycoprotein
  • MUC5
  • mucin 5, subtypes A and C, tracheobronchial/gastric
  • mucin 5AC, oligomeric mucus/gel-forming pseudogene
  • mucin 5AC, oligomeric mucus/gel-forming
  • mucin-5 subtype AC, tracheobronchial
  • mucin-5AC
  • TBM
  • tracheobronchial mucin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Mucin 5AC Antibody (NBP2-32732G) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-32732AF350
Alexa Fluor 405 NBP2-32732AF405
Alexa Fluor 488 NBP2-32732AF488
Alexa Fluor 532 NBP2-32732AF532
Alexa Fluor 594 NBP2-32732AF594
Alexa Fluor 647 NBP2-32732AF647
Alexa Fluor 700 NBP2-32732AF700
Alexa Fluor 750 NBP2-32732AF750
Allophycocyanin NBP2-32732APC
Allophycocyanin/Cy7 NBP2-32732APCCY7
Biotin NBP2-32732B
DyLight 350 NBP2-32732UV
DyLight 405 NBP2-32732V
DyLight 488 NBP2-32732G
DyLight 550 NBP2-32732R
DyLight 594 NBP2-32732DL594
DyLight 650 NBP2-32732C
DyLight 680 NBP2-32732FR
DyLight 755 NBP2-32732IR
FITC NBP2-32732F
HRP NBP2-32732H
Janelia Fluor 549 NBP2-32732JF549
Janelia Fluor 646 NBP2-32732JF646
PE NBP2-32732PE
PE/Atto594 NBP2-32732PEATT594
PE/Cy5.5 NBP2-32732PECY55
PE/Cy7 NBP2-32732PECY7
PerCP NBP2-32732PCP

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol MUC5AC