MUC3 Antibody (M3.1) [Allophycocyanin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
M3.1
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

MUC3 Antibody (M3.1) [Allophycocyanin] Summary

Immunogen
A synthetic peptide of 35 amino acids, SIB35 (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS), which contains two of the MUC3 tandem repeats, coupled to KLH.
Localization
Cytoplasmic and cell surface
Specificity
It recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3). Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. MUC3 is distributed in colon and rectum, and is also present to a lesser extent in breast, lung and salivary gland tissues. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MUC3A
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody shomld be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MUC3 Antibody (M3.1) [Allophycocyanin]

  • MUC-3A
  • mucin 3, intestinal
  • mucin 3A, cell surface associated
  • mucin 3A, intestinal
  • mucin-3A

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics Tool for MUC3 Antibody (NBP2-47686APC)

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Diseases for MUC3 Antibody (NBP2-47686APC)

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Bioinformatics

Gene Symbol MUC3A
Uniprot