MTBP Antibody

Images

 
Western Blot: MTBP Antibody [NBP1-76747] - Analysis of MTBP expression in K562 cell lysate with MTBP antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: MTBP Antibody [NBP1-76747] - Immunofluorescence of MTBP in K562 cells with MTBP antibody at 20 ug/mL.
Western Blot: MTBP Antibody [NBP1-76747] - Analysis of MTBP expression in K562 whole cell lysates with anti-MTBP using this antibody at 1 ug /ml.
Immunocytochemistry/ Immunofluorescence: MTBP Antibody [NBP1-76747] - K562 cells with MTBP antibody at 5 ug/ml.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

MTBP Antibody Summary

Immunogen
Antibody was raised against a 18 amino acid peptide near the center of human MTBP. The immunogen is located within amino acids 110 - 160 of MTBP. Amino Acid Squence: GAVECFEEEDSNSRESLS
Predicted Species
Mouse (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MTBP
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 5-20 ug/ml
  • Western Blot 1-2 ug/ml
Application Notes
MTBP antibody can be used for detection of MTBP by Western blot at 1 to 2 ug/mL. A 104 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 5ug/mL. For immunofluorescence start at 20 ug/mL.
Theoretical MW
104 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
MTBP Peptide (NBP1-76747PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Purity
Peptide affinity purified

Alternate Names for MTBP Antibody

  • hMTBP
  • MDM2 (mouse double minute 2)-binding protein, 104kD
  • Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) bindingprotein, 104kDa
  • mdm2-binding protein
  • MDM2BP

Background

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2 and MTBP, were recently discovered. The transcriptional activity of p53 is modulated by posttranslational regulations of the p53 protein including stabilization and acetylation. P53 transcriptionally activates MDM2 gene then the translated MDM2 protein binds to p53 and promotes the degradation of p53 leading to lowering the concentration of p53 protein. MDM2 inhibits both p53 mediated G1 arrest and apoptosis. A recently discovered protein termed MTBP was found to bind to MDM2 and to inhibit the modulation effect of MDM2 on p53. MTBP is expressed in a variety of normal tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB100-2736
Species: Hu, Mu, Rt
Applications: IHC, IHC-Fr, IHC-P, IP, WB
NB200-103
Species: Hu, Mu, Rt, Xp(-), Ye
Applications: CyTOF-ready, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
NB100-56506
Species: Ma, Hu, Mar, Mu, Rt
Applications: ChIP, CyTOF-ready, ELISA, Flow, IB, ICC/IF, IHC, IHC-Fr, IHC-P, IP, PLA, Simple Western, WB
NB200-106
Species: Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, WB
NBP1-31133
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
NBP2-29463
Species: Pm, Hu, Pm, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, WB
NBP2-46085
Species: Hu
Applications: IHC, WB
H00027065-M01
Species: Hu, Rt
Applications: ELISA, ICC/IF, S-ELISA, WB
NBP2-52452
Species: Hu
Applications: CyTOF-ready, ELISA, Flow, IHC, IHC-P, WB
H00001059-B01P
Species: Hu
Applications: ICC/IF, WB
NBP2-21037
Species: Hu
Applications: IHC, IHC-P, WB
NBP2-31361
Species: Hu
Applications: IHC, IHC-P, WB
NBP1-81988
Species: Hu
Applications: IHC, IHC-P
NB600-302
Species: Bv, Dr, Hu, Mu
Applications: ChIP, ELISA, Flow-IC, Flow, IB, ICC/IF, IHC, IHC-Fr, IHC-P, IP, PLA, S-ELISA, Simple Western, WB
DVE00
Species: Hu
Applications: ELISA
NB100-563
Species: Hu
Applications: ICC/IF, IHC, IHC-P, IP, WB
NB200-351
Species: Ha, Hu, Mu
Applications: IHC, IHC-P, IP, WB
NBP1-90149
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB

Publications for MTBP Antibody (NBP1-76747) (0)

There are no publications for MTBP Antibody (NBP1-76747).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for MTBP Antibody (NBP1-76747) (0)

There are no reviews for MTBP Antibody (NBP1-76747). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for MTBP Antibody (NBP1-76747) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional MTBP Products

Bioinformatics Tool for MTBP Antibody (NBP1-76747)

Discover related pathways, diseases and genes to MTBP Antibody (NBP1-76747). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for MTBP Antibody (NBP1-76747)

Discover more about diseases related to MTBP Antibody (NBP1-76747).
 

Pathways for MTBP Antibody (NBP1-76747)

View related products by pathway.

PTMs for MTBP Antibody (NBP1-76747)

Learn more about PTMs related to MTBP Antibody (NBP1-76747).
 

Research Areas for MTBP Antibody (NBP1-76747)

Find related products by research area.

Blogs on MTBP

There are no specific blogs for MTBP, but you can read our latest blog posts.
Omicron Variant Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our MTBP Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol MTBP
Uniprot