MSX2 Antibody (786607) [FITC]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 786607
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

MSX2 Antibody (786607) [FITC] Summary

• Immunogen: E. coli-derived recombinant human MSX2
  Ala2-Thr132
  Accession # P35548
• Specificity: Detects human MSX2 in ELISAs. In direct ELISAs, no cross-reactivity with recombinant human MSX1 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MSX2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for MSX2 Antibody (786607) [FITC]

• CRS2
• CRS2parietal foramina 1
• FPP
• Homeobox protein Hox-8
• homeobox protein MSX-2
• Hox8
• HOX8msh homeobox homolog 2 (Drosophila)
• msh (Drosophila) homeo box homolog 2
• msh homeo box 2
• msh homeobox 2
• msh homeobox homolog 2
• MSH
• MSX2
• PFM
• PFM1

Background

Msx2/Hox8 encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MSX2