MSX1 Antibody [Unconjugated]

Images

 
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line. Gels were loaded with 30 μg of whole cell lysate (WCL), 20 μg of cytoplasmic (Cyto), and 10 μg of nuclear extracts (Nuc). PVDF ...read more
MSX1 was detected in immersion fixed paraffin-embedded sections of human ovarian cancer tissue using Goat Anti-Human/Mouse MSX1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5045) at 0.3, 1.0 and 3.0 µg/mL ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

MSX1 Antibody [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human MSX1
Met1-Thr165
Accession # P28360
Specificity
Detects human and mouse MSX1 in Western blots.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
MSX1
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-15 ug/mL
  • Western Blot 0.1 ug/mL
Publications
Read Publications using
AF5045 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MSX1 Antibody [Unconjugated]

  • Homeobox protein Hox-7
  • homeobox protein MSX-1
  • HOX7
  • HOX7homeobox 7
  • HYD1
  • HYD1msh homeobox homolog 1 (Drosophila)
  • msh (Drosophila) homeo box homolog 1 (formerly homeo box 7)
  • msh homeo box 1
  • msh homeobox 1
  • Msh homeobox 1-like protein
  • msh homeobox homolog 1
  • MSX1
  • OFC5
  • STHAG1

Background

MSX1 (Msh homeobox homology 1) is a member of the muscle segment homoebox gene family. MSX1 is involved in limb-pattern formation, craniofacial development, odontogenesis, and tumor growth inhibition. MSX1 functions as a transcriptional repressor. MSX1 has been shown to interact with the linker histone, H1B, and repress transcription of the MyoD promoter. Chromosomal abnormalities involving MSX1 have been associated with the Wolf-Hirschhorn syndrome characterized by heart defects and mental retardation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MSX1 Antibody (AF5045)(6)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: ICC, IHC, Western Blot.


Filter By Application
ICC
(1)
IHC
(2)
Western Blot
(3)
All Applications
Filter By Species
Human
(5)
Mouse
(1)
All Species
Showing Publications 1 - 6 of 6.
Publications using AF5045 Applications Species
W Chiu, A Li, T Wang, W Li, X Zhang Generation of a MSX1 knockout human embryonic stem cell line using CRISPR/Cas9 technology Stem Cell Research, 2022;60(0):102729. 2022 [PMID: 35247841] (ICC, Human) ICC Human
X Hu, C Lin, N Ruan, Z Huang, Y Zhang, X Hu Operation of the Atypical Canonical Bone Morphogenetic Protein Signaling Pathway During Early Human Odontogenesis Frontiers in Physiology, 2022;13(0):823275. 2022 [PMID: 35211032] (Western Blot, Human) Western Blot Human
S Heino, S Fang, M Lähde, J Högström, S Nassiri, A Campbell, D Flanagan, A Raven, M Hodder, N Nasreddin, HH Xue, M Delorenzi, S Leedham, TV Petrova, O Sansom, K Alitalo Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas Science Advances, 2021;7(47):eabj0512. 2021 [PMID: 34788095] (IHC, Mouse) IHC Mouse
L Pellegrini, A Albecka, DL Mallery, MJ Kellner, D Paul, AP Carter, LC James, MA Lancaster SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids Cell Stem Cell, 2020;0(0):. 2020 [PMID: 33113348] (IHC, Human) IHC Human
M Horazna, L Janeckova, J Svec, O Babosova, D Hrckulak, M Vojtechova, K Galuskova, E Sloncova, M Kolar, H Strnad, V Korinek Msx1 loss suppresses formation of the ectopic crypts developed in the Apc-deficient small intestinal epithelium Sci Rep, 2019;9(1):1629. 2019 [PMID: 30733598] (Western Blot, Human) Western Blot Human
A Sancho, I Vandersmis, S Craps, A Luttun, J Groll A new strategy to measure intercellular adhesion forces in mature cell-cell contacts Sci Rep, 2017;7(0):46152. 2017 [PMID: 28393890] (Western Blot, Human) Western Blot Human

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Bioinformatics

Gene Symbol MSX1
Uniprot