Mouse Neutrophil Elastase/ELA2 DuoSet ELISA, 5 Plate



Product Details

Reactivity MuSpecies Glossary
Applications ELISA

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Mouse Neutrophil Elastase/ELA2 DuoSet ELISA, 5 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using
DY4517-05 in the following applications:

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse Neutrophil Elastase/ELA2 DuoSet ELISA, 5 Plate

  • Bone marrow serine protease
  • EC 3.4.21
  • EC
  • ELA2
  • ELA2granulocyte-derived elastase
  • elastase 2, neutrophil
  • elastase, neutrophil expressed
  • Elastase-2
  • GE
  • HLEelastase-2
  • HNE
  • Human leukocyte elastase
  • Leukocyte Elastase
  • Medullasin
  • NE
  • Neutrophil Elastase
  • PMN elastase
  • PMN-E
  • polymorphonuclear elastase
  • SCN1


Neutrophil Elastase (ELA2), also known as polymorphonuclear leukocyte elastase, is a serine protease belonging to the chymotrypsin family. Located primarily in the azurophil granules of polymorphonuclear leukocytes, ELA2 function results in the degradation of many extracellular matrix macromolecules. Alpha-1 Antitrypsin (Serpin A1) and secretory leukocyte protease inhibitor (SLPI) have been shown to inhibit ELA2 activity. ELA2 may be involved in lung emphysema, cystic fibrosis, the adult respiratory distress syndrome (ARDS), rheumatoid arthritis, tumor invasion and infectious diseases.

Publications for Neutrophil Elastase/ELA2 (DY4517-05)(14)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Transgenic Mouse.

We have publications tested in 1 application: ELISA.

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Showing Publications 1 - 10 of 14. Show All 14 Publications.
Publications using DY4517-05 Applications Species
M Costa Fuji, A Yazdanpana, S Horne, A Lamont, P Lopez, C Farr Zuend, K Birse, M Taverner, R Greenslade, M Abou, L Noel-Romas, B Abrenica, O Ajibola, N Ikeogu, RC Su, LR McKinnon, H Pymar, V Poliquin, AR Berard, A Burgener, TT Murooka Non-optimal bacteria species induce neutrophil-driven inflammation and barrier disruption in the female genital tract Mucosal Immunology, 2023-04-29;0(0):. 2023-04-29 [PMID: 37121385] (ELISA, Mouse) ELISA Mouse
J Zhao, N Zhen, Q Zhou, J Lou, W Cui, G Zhang, B Tian NETs Promote Inflammatory Injury by Activating cGAS-STING Pathway in Acute Lung Injury International Journal of Molecular Sciences, 2023-03-07;24(6):. 2023-03-07 [PMID: 36982193] (Mouse) Mouse
P Kumar, A Mittal, P Bansal, S Aggarwal, RK Rajnish, A Dadra, S Sharma Wound alpha defensin levels are significantly higher in patients with fracture related infection: A pilot, prospective cohort study Injury, 2022-12-13;0(0):. 2022-12-13 [PMID: 36567156] (Human) Human
RA Keogh, AL Haeberle, CJ Langouët-A, JS Kavanaugh, EP Schmidt, GD Moore, AR Horswill, KS Doran Group B Streptococcus adaptation promotes survival in a hyperinflammatory diabetic wound environment Science Advances, 2022-11-11;8(45):eadd3221. 2022-11-11 [PMID: 36367946] (Mouse, Transgenic Mouse) Mouse, Transgenic Mouse
A Gupta, K Singh, S Fatima, S Ambreen, S Zimmermann, R Younis, S Krishnan, R Rana, I Gadi, C Schwab, R Biemann, K Shahzad, V Rani, S Ali, PR Mertens, S Kohli, B Isermann Neutrophil Extracellular Traps Promote NLRP3 Inflammasome Activation and Glomerular Endothelial Dysfunction in Diabetic Kidney Disease Nutrients, 2022-07-20;14(14):. 2022-07-20 [PMID: 35889923] (Mouse) Mouse
KC Ngamsri, RA Putri, C Jans, K Schindler, A Fuhr, Y Zhang, J Gamper-Tsi, S Ehnert, FM Konrad CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet-Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling International Journal of Molecular Sciences, 2021-12-17;22(24):. 2021-12-17 [PMID: 34948374] (Mouse) Mouse
P Saha, BS Yeoh, X Xiao, RM Golonka, V Singh, Y Wang, M Vijay-Kuma PAD4-dependent NETs generation are indispensable for intestinal clearance of Citrobacter rodentium Mucosal Immunol, 2019-02-01;0(0):. 2019-02-01 [PMID: 30710097] (Mouse) Mouse
S Aggarwal, I Ahmad, A Lam, MA Carlisle, C Li, JM Wells, SV Raju, M Athar, SM Rowe, MT Dransfield, S Matalon Heme scavenging reduces pulmonary endoplasmic reticulum stress, fibrosis, and emphysema JCI Insight, 2018-11-02;3(21):. 2018-11-02 [PMID: 30385726] (Mouse) Mouse
S Al-Salam, S Hashmi Myocardial Ischemia Reperfusion Injury: Apoptotic, Inflammatory and Oxidative Stress Role of Galectin-3 Cell. Physiol. Biochem., 2018-10-24;50(3):1123-1139. 2018-10-24 [PMID: 30355930] (Mouse) Mouse
P Ochieng, S Nath, R Macarulay, E Eden, A Dabo, M Campos, XC Jiang, RF Foronjy, P Geraghty Phospholipid transfer protein and alpha-1 antitrypsin regulate Hck kinase activity during neutrophil degranulation Sci Rep, 2018-10-18;8(1):15394. 2018-10-18 [PMID: 30337619] (Mouse) Mouse
Show All 14 Publications.

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