Neutrophil Elastase/ELA2 Products

Antibodies
Neutrophil Elastase/ELA2 Anti ...
Neutrophil Elastase/ELA2 Antibody ...
MAB91671
Species: Hu
Applications: WB, IHC, CyTOF-ready, ICC, ICFlow
Host: Mouse Monoclonal
Neutrophil Elastase/ELA2 Anti ...
Neutrophil Elastase/ELA2 Antibody ...
MAB4517
Species: Mu
Applications: WB
Host: Rat Monoclonal
ELISA Kits
Neutrophil Elastase/ELA2 ELIS ...
Neutrophil Elastase/ELA2 ELISA Kit
NBP1-91266
Species: Hu
Applications: ELISA
Neutrophil Elastase/ELA2 ELIS ...
Neutrophil Elastase/ELA2 ELISA Kit...
KA1842
Species: Hu
Neutrophil Elastase/ELA2 ELIS ...
Neutrophil Elastase/ELA2 ELISA Kit...
KA1102
Lysates
Neutrophil Elastase/ELA2 Over ...
Neutrophil Elastase/ELA2 Overexpre...
NBL1-10217
Applications: WB
Proteins
Recombinant Human Neutrophil ...
Recombinant Human Neutrophil Elast...
H00001991-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Neutrophil Elastase/ELA2 RNAi ...
Neutrophil Elastase/ELA2 RNAi
H00001991-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The ELANE gene (commonly known as neutrophil elastase) encodes a 267 amino acid long, 28 kDA neutrophil elastase protein that functions in regulation of natural killer cells, monocytes, and graulocytes. ELANE is involved in activation of proMMP8, cell adhesion cell-matrix glycoconjugates, selected targets of C/EBPbeta, degradation of the extracellular matrix and collagen, and amb2 integrin signaling. It interacts with various genes GZMB, LRP1, SERPINF2, SERPING1, and SERPINA1. Elane has been linked to cystic fibrosis, asthma, pneumonia, alzheimer's disease, neutropenia, cutis laxia, leg ulcers, wegener's granulomatosis, bronchitis, adult respiratory distress syndrome, and vascular diseases.

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 1991
Alternate Names
  • EC 3.4.21
  • GE
  • Medullasin
  • SCN1
  • Elastase-2
  • PMN elastase
  • EC 3.4.21.37
  • Human leukocyte elastase
  • polymorphonuclear elastase
  • Bone marrow serine protease
  • neutrophil elastase
  • elastase 2, neutrophil
  • medullasin
  • NE
  • leukocyte elastase
  • HNE
  • ELA2granulocyte-derived elastase
  • HLEelastase-2
  • PMN-E
  • elastase, neutrophil expressed

Pathways for Neutrophil Elastase/ELA2

View related products by pathway and learn more about each of the pathways below.

Pathogenesis
Cell Proliferation
Proteolysis
Wound Healing
Neutrophil Activation

Research Areas for Neutrophil Elastase/ELA2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Neuroscience

Bioinformatics Tool for Neutrophil Elastase/ELA2

Discover related pathways, diseases and genes to Neutrophil Elastase/ELA2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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