Mouse Myeloperoxidase DuoSet ELISA, 15 Plate



Product Details

Reactivity MuSpecies Glossary
Applications ELISA

Order Details

Mouse Myeloperoxidase DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DY3667.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse Myeloperoxidase DuoSet ELISA, 15 Plate

  • EC 1.11.1
  • EC
  • Lactoperoxidase
  • MPO
  • Myeloperoxidase


Myeloperoxidase (MPO) is a heme-containing enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxide dependent formation of hypochlorus acid (HOCl) and other reactive species. Enzymatically active MPO is a disulfide-linked tetramer that contains two heme groups and two copies each of the heavy and light chains. MPO binds Albumin, MMR, Cytokeratin 1 on vascular endothelial cells, HMW Kininogen, and Integrin CD11b/CD18 on neutrophils. These interactions promote MPO clearance, a reduction of nitric oxide and bradykinin levels, reduced vasodilation, and continued neutrophil activation. Neutrophil MPO is stored in cytoplasmic azurophilic granules. Upon cellular activation and degranulation, MPO is delivered into phagosomes where it is required for the killing of phagocytosed bacteria. Activated neutrophils also release granule contents extracellularly. Elevated plasma MPO levels have been associated with a variety of clinical conditions including systemic inflammation, eclampsia, risk of cardiovascular events, vascular endothelial dysfunction, severity of multiple sclerosis, and prospective mortality and oxidative stress during hemodialysis.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Species: Hu, Mu, Rt, Po
Applications: WB, Flow, IB, ICC/IF, IHC, IHC-P, In vitro
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, Flow, IHC, CyTOF-ready, ICC
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, Flow, IHC, IHC-P, S-ELISA, CyTOF-ready
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, Simple Western, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ICFlow, Neut, ELISA(Sta)
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Species: Hu, Mu, Bv, Gt, Sh
Applications: WB
Species: Hu, Mu
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-P
Species: Mu
Applications: ELISA

Publications for Myeloperoxidase/MPO (DY3667)(40)

We have publications tested in 2 confirmed species: Mouse, Rat.

Filter By Application
All Applications
Filter By Species
All Species
Showing Publications 1 - 10 of 40. Show All 40 Publications.
Publications using DY3667 Applications Species
NE Powers, B Swartzwelt, C Marchetti, DM de Graaf, A Lerchner, M Schlapschy, R Datar, U Binder, CK Edwards, A Skerra, CA Dinarello PASylation of IL-1 Receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis J. Biol. Chem., 2019;0(0):. 2019 [PMID: 31819009] (Mouse) Mouse
J Nagai, B Balestrier, LB Fanning, T Kyin, H Cirka, J Lin, M Idzko, A Zech, EY Kim, PJ Brennan, JA Boyce P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation J. Clin. Invest., 2019;0(0):. 2019 [PMID: 31638598] (Mouse) Mouse
SL Wang, BZ Shao, SB Zhao, X Chang, P Wang, CY Miao, ZS Li, Y Bai Intestinal autophagy links psychosocial stress with gut microbiota to promote inflammatory bowel disease Cell Death Dis, 2019;10(6):391. 2019 [PMID: 31564717]
S Tariket, H Hamzeh-Cog, S Laradi, CA Arthaud, MA Eyraud, T Bourlet, P Berthelot, O Garraud, F Cognasse Evidence of CD40L/CD40 pathway involvement in experimental transfusion-related acute lung injury Sci Rep, 2019;9(1):12536. 2019 [PMID: 31467410] (Mouse) Mouse
J Yang, I Ramirez Mo, C van 't Vee, AF de Vos, R de Beer, JJTH Roelofs, BP Morgan, T van der Po Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model Respir. Res., 2019;20(1):165. 2019 [PMID: 31340811] (Mouse) Mouse
PR Randad, CA Dillen, RV Ortines, D Mohr, M Aziz, LB Price, H Kaya, J Larsen, KC Carroll, TC Smith, LS Miller, CD Heaney Comparison of livestock-associated and community-associated Staphylococcus aureus pathogenicity in a mouse model of skin and soft tissue infection Sci Rep, 2019;9(1):6774. 2019 [PMID: 31043631] (Mouse) Mouse
SX Li, S Sen, JM Schneider, KN Xiong, NM Nusbacher, N Moreno-Hui, M Shaffer, AJS Armstrong, E Severs, K Kuhn, CP Neff, M McCarter, T Campbell, CA Lozupone, BE Palmer Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection PLoS Pathog., 2019;15(4):e1007611. 2019 [PMID: 30947289] (Mouse) Mouse
KD Triplett, S Pokhrel, MJ Castleman, SM Daly, BO Elmore, JA Joyner, G Sharma, G Herbert, MJ Campen, HJ Hathaway, ER Prossnitz, PR Hall GPER activation protects against epithelial barrier disruption by Staphylococcus aureus ?-toxin Sci Rep, 2019;9(1):1343. 2019 [PMID: 30718654] (Mouse) Mouse
P Saha, BS Yeoh, X Xiao, RM Golonka, V Singh, Y Wang, M Vijay-Kuma PAD4-dependent NETs generation are indispensable for intestinal clearance of Citrobacter rodentium Mucosal Immunol, 2019;0(0):. 2019 [PMID: 30710097] (Mouse) Mouse
H Cui, S Banerjee, S Guo, N Xie, J Ge, D Jiang, M Zörnig, VJ Thannickal, G Liu Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury JCI Insight, 2019;0(0):. 2019 [PMID: 30676324] (Mouse) Mouse
Show All 40 Publications.

Reviews for Myeloperoxidase/MPO (DY3667) (0)

There are no reviews for Myeloperoxidase/MPO (DY3667). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Myeloperoxidase/MPO (DY3667). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

Biotin DY3667

Additional Myeloperoxidase/MPO Products

Bioinformatics Tool for Myeloperoxidase/MPO (DY3667)

Discover related pathways, diseases and genes to Myeloperoxidase/MPO (DY3667). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Myeloperoxidase/MPO (DY3667)

Discover more about diseases related to Myeloperoxidase/MPO (DY3667).

Pathways for Myeloperoxidase/MPO (DY3667)

View related products by pathway.

PTMs for Myeloperoxidase/MPO (DY3667)

Learn more about PTMs related to Myeloperoxidase/MPO (DY3667).

Blogs on Myeloperoxidase/MPO

There are no specific blogs for Myeloperoxidase/MPO, but you can read our latest blog posts.
Coronavirus Brochure

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Review this Product

Be the first to review our Mouse Myeloperoxidase DuoSet ELISA, 15 Plate and receive a gift card or discount.


Gene Symbol Mpo