Mouse Myeloperoxidase DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Mouse Myeloperoxidase DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Mpo

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY3667.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse Myeloperoxidase DuoSet ELISA, 15 Plate

  • EC 1.11.1
  • EC 1.11.1.7
  • Lactoperoxidase
  • MPO
  • Myeloperoxidase

Background

Myeloperoxidase (MPO) is a heme-containing enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxide dependent formation of hypochlorus acid (HOCl) and other reactive species. Enzymatically active MPO is a disulfide-linked tetramer that contains two heme groups and two copies each of the heavy and light chains. MPO binds Albumin, MMR, Cytokeratin 1 on vascular endothelial cells, HMW Kininogen, and Integrin CD11b/CD18 on neutrophils. These interactions promote MPO clearance, a reduction of nitric oxide and bradykinin levels, reduced vasodilation, and continued neutrophil activation. Neutrophil MPO is stored in cytoplasmic azurophilic granules. Upon cellular activation and degranulation, MPO is delivered into phagosomes where it is required for the killing of phagocytosed bacteria. Activated neutrophils also release granule contents extracellularly. Elevated plasma MPO levels have been associated with a variety of clinical conditions including systemic inflammation, eclampsia, risk of cardiovascular events, vascular endothelial dysfunction, severity of multiple sclerosis, and prospective mortality and oxidative stress during hemodialysis.

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DY3667
Species: Mu
Applications: ELISA

Publications for Myeloperoxidase/MPO (DY3667)(40)

We have publications tested in 2 confirmed species: Mouse, Rat.


Filter By Application
All Applications
Filter By Species
Mouse
(38)
Rat
(1)
All Species
Showing Publications 1 - 10 of 40. Show All 40 Publications.
Publications using DY3667 Applications Species
NE Powers, B Swartzwelt, C Marchetti, DM de Graaf, A Lerchner, M Schlapschy, R Datar, U Binder, CK Edwards, A Skerra, CA Dinarello PASylation of IL-1 Receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis J. Biol. Chem., 2019;0(0):. 2019 [PMID: 31819009] (Mouse) Mouse
J Nagai, B Balestrier, LB Fanning, T Kyin, H Cirka, J Lin, M Idzko, A Zech, EY Kim, PJ Brennan, JA Boyce P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation J. Clin. Invest., 2019;0(0):. 2019 [PMID: 31638598] (Mouse) Mouse
SL Wang, BZ Shao, SB Zhao, X Chang, P Wang, CY Miao, ZS Li, Y Bai Intestinal autophagy links psychosocial stress with gut microbiota to promote inflammatory bowel disease Cell Death Dis, 2019;10(6):391. 2019 [PMID: 31564717]
S Tariket, H Hamzeh-Cog, S Laradi, CA Arthaud, MA Eyraud, T Bourlet, P Berthelot, O Garraud, F Cognasse Evidence of CD40L/CD40 pathway involvement in experimental transfusion-related acute lung injury Sci Rep, 2019;9(1):12536. 2019 [PMID: 31467410] (Mouse) Mouse
J Yang, I Ramirez Mo, C van 't Vee, AF de Vos, R de Beer, JJTH Roelofs, BP Morgan, T van der Po Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model Respir. Res., 2019;20(1):165. 2019 [PMID: 31340811] (Mouse) Mouse
PR Randad, CA Dillen, RV Ortines, D Mohr, M Aziz, LB Price, H Kaya, J Larsen, KC Carroll, TC Smith, LS Miller, CD Heaney Comparison of livestock-associated and community-associated Staphylococcus aureus pathogenicity in a mouse model of skin and soft tissue infection Sci Rep, 2019;9(1):6774. 2019 [PMID: 31043631] (Mouse) Mouse
SX Li, S Sen, JM Schneider, KN Xiong, NM Nusbacher, N Moreno-Hui, M Shaffer, AJS Armstrong, E Severs, K Kuhn, CP Neff, M McCarter, T Campbell, CA Lozupone, BE Palmer Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection PLoS Pathog., 2019;15(4):e1007611. 2019 [PMID: 30947289] (Mouse) Mouse
KD Triplett, S Pokhrel, MJ Castleman, SM Daly, BO Elmore, JA Joyner, G Sharma, G Herbert, MJ Campen, HJ Hathaway, ER Prossnitz, PR Hall GPER activation protects against epithelial barrier disruption by Staphylococcus aureus ?-toxin Sci Rep, 2019;9(1):1343. 2019 [PMID: 30718654] (Mouse) Mouse
P Saha, BS Yeoh, X Xiao, RM Golonka, V Singh, Y Wang, M Vijay-Kuma PAD4-dependent NETs generation are indispensable for intestinal clearance of Citrobacter rodentium Mucosal Immunol, 2019;0(0):. 2019 [PMID: 30710097] (Mouse) Mouse
H Cui, S Banerjee, S Guo, N Xie, J Ge, D Jiang, M Zörnig, VJ Thannickal, G Liu Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury JCI Insight, 2019;0(0):. 2019 [PMID: 30676324] (Mouse) Mouse
Show All 40 Publications.

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Product General Protocols

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FAQs for Myeloperoxidase/MPO (DY3667). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

Biotin DY3667

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Gene Symbol Mpo