Mouse Myeloperoxidase DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Mouse Myeloperoxidase DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Mpo

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY3667.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse Myeloperoxidase DuoSet ELISA, 15 Plate

  • EC 1.11.1
  • EC 1.11.1.7
  • MPO
  • Myeloperoxidase

Background

Myeloperoxidase (MPO) is a heme-containing enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxide dependent formation of hypochlorus acid (HOCl) and other reactive species. Enzymatically active MPO is a disulfide-linked tetramer that contains two heme groups and two copies each of the heavy and light chains. MPO binds Albumin, MMR, Cytokeratin 1 on vascular endothelial cells, HMW Kininogen, and Integrin CD11b/CD18 on neutrophils. These interactions promote MPO clearance, a reduction of nitric oxide and bradykinin levels, reduced vasodilation, and continued neutrophil activation. Neutrophil MPO is stored in cytoplasmic azurophilic granules. Upon cellular activation and degranulation, MPO is delivered into phagosomes where it is required for the killing of phagocytosed bacteria. Activated neutrophils also release granule contents extracellularly. Elevated plasma MPO levels have been associated with a variety of clinical conditions including systemic inflammation, eclampsia, risk of cardiovascular events, vascular endothelial dysfunction, severity of multiple sclerosis, and prospective mortality and oxidative stress during hemodialysis.

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Publications for Myeloperoxidase/MPO (DY3667)(61)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.


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Human
(1)
Mouse
(56)
Rat
(3)
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Showing Publications 1 - 10 of 61. Show All 61 Publications.
Publications using DY3667 Applications Species
N Kim, S Lee, J Kang, TK Kwon, D Khang, SH Kim Gomisin M2 alleviates psoriasis?like skin inflammation by inhibiting inflammatory signaling pathways Molecular Medicine Reports, 2021;24(6):. 2021 [PMID: 34664681] (Human) Human
Y Bian, J Lei, J Zhong, B Wang, Y Wan, J Li, C Liao, Y He, Z Liu, K Ito, B Zhang Kaempferol Reduces Obesity, Prevents Intestinal Inflammation, and Modulates Gut Microbiota in High-fat Diet Mice: Kaempferol reduce inflammation and dysbacteria The Journal of nutritional biochemistry, 2021;0(0):108840. 2021 [PMID: 34419569] (Mouse) Mouse
SL Puhl, M Hilby, M Kohlhaas, LM Keidel, Y Jansen, M Hristov, J Schindler, C Maack, S Steffens Haematopoietic and cardiac GPR55 synchronize post-myocardial infarction remodelling Scientific Reports, 2021;11(1):14385. 2021 [PMID: 34257332] (Mouse) Mouse
A Doni, R Parente, I Laface, E Magrini, C Cunha, FS Colombo, JF Lacerda, A Campos, SN Mapelli, F Petroni, R Porte, T Schorn, A Inforzato, T Mercier, K Lagrou, J Maertens, JD Lambris, B Bottazzi, C Garlanda, M Botto, A Carvalho, A Mantovani Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus Nature Communications, 2021;12(1):3739. 2021 [PMID: 34145258] (Mouse) Mouse
A Ulu, A Burr, AJ Heires, J Pavlik, T Larsen, PA Perez, C Bravo, NV DiPatrizio, M Baack, DJ Romberger, TM Nordgren A high docosahexaenoic acid diet alters lung inflammation and recovery following repetitive exposure to aqueous organic dust extracts: Role of DHA in repetitive organic dust exposure The Journal of nutritional biochemistry, 2021;0(0):108797. 2021 [PMID: 34126202] (Mouse) Mouse
M Dupuit, V Chavanelle, B Chassaing, F Perriere, M Etienne, C Plissonnea, A Boscaro, N Barnich, V Pialoux, T Maugard, F Le Joubiou, S Peltier, P Sirvent, YF Otero, N Boisseau The TOTUM-63 Supplement and High-Intensity Interval Training Combination Limits Weight Gain, Improves Glycemic Control, and Influences the Composition of Gut Mucosa-Associated Bacteria in Rats on a High Fat Diet Nutrients, 2021;13(5):. 2021 [PMID: 34066988] (Rat) Rat
T Lin, D Quellier, J Lamb, T Voisin, P Baral, F Bock, A Schönberg, R Mirchev, G Pier, I Chiu, M Gadjeva Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection PloS Pathogens, 2021;17(5):e1009557. 2021 [PMID: 33956874] (Mouse) Mouse
G Cavalli, IW Tengesdal, M Gresnigt, T Nemkov, RJW Arts, J Domínguez-, R Molteni, D Stefanoni, E Cantoni, L Cassina, S Giugliano, K Schraa, TS Mills, EM Pietras, EZ Eisenmenss, L Dagna, A Boletta, A D'Alessand, LAB Joosten, MG Netea, CA Dinarello The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity Cell Reports, 2021;35(1):108955. 2021 [PMID: 33826894] (Mouse) Mouse
NV Bogatcheva, ME Coleman Concentrated Secretome of Adipose Stromal Cells Limits Influenza A Virus-Induced Lung Injury in Mice Cells, 2021;10(4):. 2021 [PMID: 33804896] (Mouse) Mouse
S Li, T Wang, B Wu, W Fu, B Xu, RR Pamuru, M Kennett, JKP Vanamala, L Reddivari Anthocyanin-containing Purple Potatoes Ameliorate DSS-induced Colitis in Mice The Journal of nutritional biochemistry, 2021;0(0):108616. 2021 [PMID: 33705951] (Mouse) Mouse
Show All 61 Publications.

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Bioinformatics

Gene Symbol Mpo