Mouse IL-23 Quantikine ELISA Kit

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse IL-23 Quantikine ELISA Kit Summary

Background
The Quantikine Mouse IL-23 immunoassay is a 4.5 hour solid-phase ELISA designed to measure IL-23 in cell culture supernates, mouse serum, and plasma. It contains Sf 21-expressed recombinant mouse IL-23 and antibodies raised against the recombinant p19 and p40 subunits. This immunoassay has been shown to accurately quantitate the recombinant mouse IL-23. Results obtained using natura...l mouse IL-23 showed dose response curves that were parallel to the standard curves obtained using the Quantikine mouse kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-23.
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Specificity
Natural and recombinant mouse IL-23. This assay does not recognize free p19 or p40 subunits.
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il23a

Applications/Dilutions

Application Notes
Interference observed with 1 or more available related molecules.
Publications
Read Publications using M2300.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-23 Quantikine ELISA Kit

  • IL-23 p19/IL-12 p40
  • IL23
  • IL-23
  • IL-23A
  • IL-23-A
  • IL-23p19
  • IL-23p19/IL-12p40
  • IL23P19P19
  • interleukin 23 p19 subunit
  • interleukin 23, alpha subunit p19
  • interleukin-23 subunit alpha
  • Interleukin-23 subunit p19
  • JKA3 induced upon T-cell activation
  • MGC79388
  • SGRF
  • SGRFIL-23 subunit alpha

Background

IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for IL-23A/IL-23 P19 (M2300)(20)

We have publications tested in 1 confirmed species: Mouse.


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Mouse
(20)
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Showing Publications 1 - 10 of 20. Show All 20 Publications.
Publications using M2300 Applications Species
M Nakao, T Miyagaki, M Sugaya, S Sato Exacerbated Imiquimod-Induced Psoriasis-Like Skin Inflammation in IRF5-Deficient Mice Int J Mol Sci, 2020;21(10):. 2020 [PMID: 32456211] (Mouse) Mouse
M Chen, J Peng, Q Xie, N Xiao, X Su, H Mei, Y Lu, J Zhou, Y Dai, S Wang, C Li, G Lin, L Cheng Mesenchymal Stem Cells Alleviate Moderate-to-Severe Psoriasis by Reducing the Production of Type I Interferon (IFN-I) by Plasmacytoid Dendritic Cells (pDCs) Stem Cells Int, 2019;2019(0):6961052. 2019 [PMID: 31827531] (Mouse) Mouse
K Kobayashi, Y Honme, T Sashihara Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 Induce the Expression of the REG3 Family in the Small Intestine of Mice via the Stimulation of Dendritic Cells and Type 3 Innate Lymphoid Cells Nutrients, 2019;11(12):. 2019 [PMID: 31817820] (Mouse) Mouse
S Doppalapud, A Jain, W Khan, AJ Domb Fenoldopam mesylate for treating psoriasis: A new indication for an old drug Int J Pharm, 2019;0(0):118726. 2019 [PMID: 31715365] (Mouse) Mouse
N Ju, M Shimamura, H Hayashi, Y Ikeda, S Yoshida, A Nakamura, R Morishita, H Rakugi, H Nakagami Preventative effects of the partial RANKL peptide MHP1-AcN in a mouse model of imiquimod-induced psoriasis Sci Rep, 2019;9(1):15434. 2019 [PMID: 31659208] (Mouse) Mouse
J Zhang, H Li, Q Wu, Y Chen, Y Deng, Z Yang, L Zhang, B Liu Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth Redox Biol, 2019;22(0):101116. 2019 [PMID: 30769285] (Mouse) Mouse
YH Kwon, H Wang, E Denou, JE Ghia, L Rossi, ME Fontes, SP Bernier, MS Shajib, S Banskota, SM Collins, MG Surette, WI Khan Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis Cell Mol Gastroenterol Hepatol, 2019;0(0):. 2019 [PMID: 30716420] (Mouse) Mouse
H Zhu, F Lou, Q Yin, Y Gao, Y Sun, J Bai, Z Xu, Z Liu, W Cai, F Ke, L Zhang, H Zhou, H Wang, G Wang, X Chen, H Zhang, Z Wang, F Ginhoux, C Lu, B Su, H Wang RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease EMBO Mol Med, 2017;9(5):589-604. 2017 [PMID: 28377495] (Mouse) Mouse
Guerra E, Lee C, Specht C, Yadav B, Huang H, Akalin A, Huh J, Mueller C, Levitz S Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma. PLoS Pathog, 0;13(1):e1006175. 0 [PMID: 28095479] (Mouse) Mouse
Lees J, Duffy S, Perera C, Moalem-Taylor G Depletion of Foxp3+ regulatory T cells increases severity of mechanical allodynia and significantly alters systemic cytokine levels following peripheral nerve injury. Cytokine, 2015;71(2):207-14. 2015 [PMID: 25461400] (Mouse) Mouse
Show All 20 Publications.

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Product General Protocols

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FAQs for IL-23A/IL-23 P19 (M2300). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP M2300

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Bioinformatics

Gene Symbol Il23a