Mouse IL-23 DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Mouse IL-23 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il23a

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY1887.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-23 DuoSet ELISA, 15 Plate

  • IL-23 p19/IL-12 p40
  • IL23
  • IL-23
  • IL-23A
  • IL-23-A
  • IL-23p19
  • IL-23p19/IL-12p40
  • IL23P19P19
  • interleukin 23 p19 subunit
  • interleukin 23, alpha subunit p19
  • interleukin-23 subunit alpha
  • Interleukin-23 subunit p19
  • JKA3 induced upon T-cell activation
  • MGC79388
  • SGRF
  • SGRFIL-23 subunit alpha

Background

IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.

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Publications for IL-23A/IL-23 P19 (DY1887)(13)

We have publications tested in 2 confirmed species: Human, Mouse.


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Human
(1)
Mouse
(12)
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Showing Publications 1 - 10 of 13. Show All 13 Publications.
Publications using DY1887 Applications Species
Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy Nat Commun, 2016;7(0):13894. 2016 [PMID: 28004802] (Mouse) Mouse
Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype Sci Rep, 2016;6(0):29712. 2016 [PMID: 27431276] (Human) Human
Brown A, Murphy A, Lalor S, Leech J, O'Keeffe K, Mac Aogain M, O'Halloran D, Lacey K, Tavakol M, Hearnden C, Fitzgerald-Hughes D, Humphreys H, Fennell J, van Wamel W, Foster T, Geoghegan J, Lavelle E, Rogers T, McLoughlin R Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection. PLoS Pathog, 2015;11(11):e1005226. 2015 [PMID: 26539822] (Mouse) Mouse
Cowardin C, Kuehne S, Buonomo E, Marie C, Minton N, Petri W Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile. MBio, 2015;6(1):. 2015 [PMID: 25626905] (Mouse) Mouse
Macho-Fernandez E, Koroleva E, Spencer C, Tighe M, Torrado E, Cooper A, Fu Y, Tumanov A Lymphotoxin beta receptor signaling limits mucosal damage through driving IL-23 production by epithelial cells. Mucosal Immunol, 0;8(2):403-13. 0 [PMID: 25183367] (Mouse) Mouse
McCarthy M, Zhu L, Procario M, Weinberg J IL-17 contributes to neutrophil recruitment but not to control of viral replication during acute mouse adenovirus type 1 respiratory infection. Virology, 2014;456(0):259-67. 2014 [PMID: 24889245] (Mouse) Mouse
Murphy A, O'Keeffe K, Lalor S, Maher B, Mills K, McLoughlin R Staphylococcus aureus infection of mice expands a population of memory gammadelta T cells that are protective against subsequent infection. J Immunol, 2014;192(8):3697-708. 2014 [PMID: 24623128] (Mouse) Mouse
Selvanantham T, Escalante N, Cruz Tleugabulova M, Fieve S, Girardin S, Philpott D, Mallevaey T Nod1 and Nod2 enhance TLR-mediated invariant NKT cell activation during bacterial infection. J Immunol, 2013;191(11):5646-54. 2013 [PMID: 24163408] (Mouse) Mouse
Kohler T, Reizis B, Johnson RS, Weighardt H, Forster I Influence of hypoxia-inducible factor 1-alpha on dendritic cell differentiation and migration. Eur. J. Immunol., 2012;42(5):1226-36. 2012 [PMID: 22539295] (Mouse) Mouse
Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection. Infect. Immun., 2012;80(1):100-9. 2012 [PMID: 22025515] (Mouse) Mouse
Show All 13 Publications.

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Product General Protocols

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FAQs for IL-23A/IL-23 P19 (DY1887). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

Biotin DY1887
Biotin DY1887

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Bioinformatics

Gene Symbol Il23a