WB, IHC, IP, CyTOF-ready, ICC, ICFlow, NeutHost:
IP, ELISA(Cap), NeutHost:
Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by TCRalpha/beta+ CD4 CD8 thymocytes, as well as by activated CD4+ and CD4+ CD45RO+ memory T cells (1). IL-17 stimulates the expression of TNFalpha, IL-1 beta, IL-6, and IL-8 (2). In addition, IL-17 is involved in the induction of inducible nitric oxide synthase and cyclooxygenase 2 in chondrocytes (3). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis (4).
|Product By Gene ID
- interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
- CTLA8cytotoxic T-lymphocyte-associated serine esterase 8
- IL-17Acytotoxic T-lymphocyte-associated protein 8
- Cytotoxic T-lymphocyte-associated antigen 8
- interleukin 17A
Bioinformatics Tool for IL-17/IL-17A
Discover related pathways, diseases and genes to IL-17/IL-17A. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.