Mouse IL-10 Quantikine ELISA Kit, 2 Plate



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Reactivity MuSpecies Glossary
Applications ELISA

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Mouse IL-10 Quantikine ELISA Kit, 2 Plate Summary

The Quantikine Mouse IL-10 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse IL-10 in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant mouse IL-10 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse IL-10 accurately. Results obtained using natural mouse IL-1...0 showed dose response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-10.
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Natural and recombinant mouse IL-10
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See PDF Datasheet for details
Spike Recovery
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Sample Volume
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Application Notes
No significant interference observed with available related molecules.
Read Publications using
M1000B in the following applications:

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-10 Quantikine ELISA Kit, 2 Plate

  • CSIF
  • CSIFMGC126450
  • Cytokine synthesis inhibitory factor
  • IL10
  • IL-10
  • IL10A
  • IL-10MGC126451
  • interleukin 10
  • interleukin-10
  • TGIF


Interleukin-10 functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for IL-10 (M1000B)(179)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: ELISA Capture.

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Showing Publications 1 - 10 of 179. Show All 179 Publications.
Publications using M1000B Applications Species
A Tanaka, S Kanmura, Y Morinaga, K Kawabata, S Arima, F Sasaki, Y Nasu, S Tanoue, S Hashimoto, M Takeshita, S Takeda, A Ido Oral administration of Lactobacillus�plantarum 06CC2 prevents experimental colitis in mice via an anti?inflammatory response Mol Med Rep, 2020;0(0):. 2020 [PMID: 31922249] (Mouse) Mouse
M Chen, J Peng, Q Xie, N Xiao, X Su, H Mei, Y Lu, J Zhou, Y Dai, S Wang, C Li, G Lin, L Cheng Mesenchymal Stem Cells Alleviate Moderate-to-Severe Psoriasis by Reducing the Production of Type I Interferon (IFN-I) by Plasmacytoid Dendritic Cells (pDCs) Stem Cells Int, 2019;2019(0):6961052. 2019 [PMID: 31827531] (Mouse) Mouse
C Li, J Pan, L Ye, H Xu, B Wang, H Xu, L Xu, T Hou, D Zhang Autophagy regulates the therapeutic potential of adipose-derived stem cells in LPS-induced pulmonary microvascular barrier damage Cell Death Dis, 2019;10(11):804. 2019 [PMID: 31645547] (Mouse) Mouse
W Hu, L Ma, G Yang, X Zeng, J Liu, B Cheng, T Hu, H Zhao, Z Liu Der p2?A20 DNA vaccine attenuates allergic inflammation in mice with allergic rhinitis Mol Med Rep, 2019;0(0):. 2019 [PMID: 31638224] (Mouse) Mouse
P Wang, X Qi, G Xu, J Liu, J Guo, X Li, X Ma, H Sun CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells Aging (Albany NY), 2019;11(18):7402-7415. 2019 [PMID: 31557129] (Mouse) Mouse
T Ondee, J Gillen, P Visitchana, P Somparn, J Issara-Amp, C Dang Phi, W Chancharoe, D Gurusamy, A Nita-Lazar, A Leelahavan Lipocalin-2 (Lcn-2) Attenuates Polymicrobial Sepsis with LPS Preconditioning (LPS Tolerance) in FcGRIIb Deficient Lupus Mice Cells, 2019;8(9):. 2019 [PMID: 31514375] (Mouse) Mouse
PAM Cavalcante, N Alenina, A Budu, LC Freitas-Li, T Alves-Silv, JSH Agudelo, F Qadri, NOS Camara, M Bader, RC Araújo Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein Mediators Inflamm., 2019;2019(0):9086758. 2019 [PMID: 31360120] (Mouse) Mouse
GCC Weis, CE Assmann, FC Cadoná, BDSR Bonadiman, AO Alves, AK Machado, MMMF Duarte, IBM da Cruz, IH Costabeber Immunomodulatory effect of mancozeb, chlorothalonil, and thiophanate methyl pesticides on macrophage cells Ecotoxicol. Environ. Saf., 2019;182(0):109420. 2019 [PMID: 31299472] (Mouse) Mouse
VV Kurilin, JN Khantakova, VP Tereschenk, JA Lopatnikov, IA Obleukhova, SV Sennikov The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA Mice J Immunol Res, 2019;2019(0):7029726. 2019 [PMID: 31143783] (Mouse) Mouse
HH Guo, CL Feng, WX Zhang, ZG Luo, HJ Zhang, TT Zhang, C Ma, Y Zhan, R Li, S Wu, Z Abliz, C Li, XL Li, XL Ma, LL Wang, WS Zheng, YX Han, JD Jiang Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases Nat Commun, 2019;10(1):1981. 2019 [PMID: 31040273] (Mouse) Mouse
Show All 179 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for IL-10 (M1000B). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP M1000B
HRP M1000B
HRP M1000B

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Bioinformatics Tool for IL-10 (M1000B)

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Blogs on IL-10.

Success of combined IL-10 and IL-12 therapy in colon cancer depends on IFN-gamma and gut barrier integrity
By Jamshed Arslan, Pharm. D., PhD. Colon cancer is responsible for over 600,000 deaths per year worldwide. Colon cancer can be classified into two categories: mismatch repair (MMR)-deficient and MMR-proficient cancers...  Read full blog post.

How to identify B cell subsets using flow cytometry
By Victoria OsinskiUsing flow cytometry to identify B cell subsetsIdentifying cellular subsets by flow cytometry requires careful and thorough planning in order to ensure the correct subset of cells are identified a...  Read full blog post.

PPAR gamma - An important target in human metabolism
Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells by interacting with members of the nuclear hormone receptor superfamily known as peroxisome proliferator activated receptors (PPARs). There are f...  Read full blog post.

CD11b: Marker for a New Type of B Cell that Participates in Cell-Mediated Immunity
Think B lymphocytes just produce antibodies? Think again! Although, of course, B cells are vital for the humoral immune response, many studies in recent years have begun to uncover antibody-independent actions of B cells: regulating T cells and thus a...  Read full blog post.

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Gene Symbol Il10