IL-10 Products

Antibodies
IL-10 Antibody (JES052A5) [Un ...
IL-10 Antibody (JES052A5) [Unconju...
MAB417
Species: Mu
Applications: WB, ELISA(Cap), Neut
Host: Rat Monoclonal
IL-10 Antibody (23738) [Uncon ...
IL-10 Antibody (23738) [Unconjugated]
MAB217
Species: Hu
Applications: WB, Simple Western, Neut
Host: Mouse Monoclonal
IL-10 Antibody [Unconjugated] ...
IL-10 Antibody [Unconjugated]
AF-217-NA
Species: Hu
Applications: WB, Simple Western, IHC, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Mouse IL-10 ELISA Kit (Colori ...
Mouse IL-10 ELISA Kit (Colorimetric)
KA1038
Species: Mu
Applications: ELISA
Human IL-10 ELISA Kit (Colori ...
Human IL-10 ELISA Kit (Colorimetric)
NBP1-89871
Species: Hu
Applications: ELISA
Primate IL-10 ELISA Kit (Colo ...
Primate IL-10 ELISA Kit (Colorimet...
NBP1-92708
Species: Pm
Applications: ELISA
Lysates
IL-10 Overexpression Lysate ( ...
IL-10 Overexpression Lysate (Native)
NBL1-11895
Applications: WB
IL-10 Overexpression Lysate ( ...
IL-10 Overexpression Lysate (Denat...
H00003586-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human IL-10 Prote ...
Recombinant Human IL-10 Protein
217-IL
Species: Hu
Applications: BA
Recombinant Mouse IL-10 Prote ...
Recombinant Mouse IL-10 Protein
417-ML
Species: Mu
Applications: BA
Recombinant Viral HCMV IL-10 ...
Recombinant Viral HCMV IL-10 Protein
117-VL
Species: V
Applications: BA
RNAi
IL-10 RNAi
IL-10 RNAi
H00003586-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Human IL10 is a non glycosylated polypeptide consisting of 178 amino acids. There is 73% homology between the human and mouse IL10 proteins, however, the human IL10 acts on both human and mouse target cells, while the mouse IL10 has species specific activity. The cellular sources of IL10 are CD4+ T cells and T cell clones, thymocytes, B cells and B cell lymphomas, macrophages, mast cell lines and keratinocytes. IL10 will stimulate the growth of stem cells, mast cells and thymocytes. IL10 enhances cytotoxic T cell development, and costimulates B cell differentiation and immunoglobulin secretion. IL10 inhibits cytokine production by macrophages and suppresses macrophage class II MHC expression. The human IL10 gene is on human chromosome 1.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Mouse
Mouse
Product By Gene ID 3586
Alternate Names
  • TGIF
  • interleukin-10
  • IL10A
  • IL-10MGC126451
  • CSIFMGC126450
  • Cytokine synthesis inhibitory factor
  • interleukin 10

Research Areas for IL-10

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Apoptosis
Asthma
Cancer
Cytokine Research
Immunology
Innate Immunity

Bioinformatics Tool for IL-10

Discover related pathways, diseases and genes to IL-10. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related IL-10 Blog Posts

Check out the latest blog posts on IL-10.
PPAR gamma - An important target in human metabolism
Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells by interacting with members of the nuclear hormone receptor superfamily known as peroxisome proliferator activated receptors (PPARs). There are f...    Read more.
CD11b: Marker for a New Type of B Cell that Participates in Cell-Mediated Immunity
Think B lymphocytes just produce antibodies? Think again! Although, of course, B cells are vital for the humoral immune response, many studies in recent years have begun to uncover antibody-independent actions of B cells: regulating T cells and thus a...    Read more.
Read more IL-10 related blogs.