IL-10 Products

IL-10 Antibody (JES052A5) [Un ...
IL-10 Antibody (JES052A5) [Unconju...
Species: Mu
Applications: WB, B/N, ELISA(Cap)
Host: Rat Monoclonal
Formulation Catalog # Availability Price  
IL-10 Antibody [Unconjugated] ...
IL-10 Antibody [Unconjugated]
Species: Hu
Applications: WB, Simple Western, IHC, B/N
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
IL-10 Antibody (23738) [Uncon ...
IL-10 Antibody (23738) [Unconjugated]
Species: Hu
Applications: WB, Simple Western, B/N
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
Antibody Pairs
IL-10 Antibody Pair [HRP]
IL-10 Antibody Pair [HRP]
Species: Hu
Applications: S-ELISA
Conjugate Catalog # Availability Size Price
Human IL-10 ELISA Kit (Colori ...
Human IL-10 ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
Rat IL-10 ELISA Kit (Colorime ...
Rat IL-10 ELISA Kit (Colorimetric)
Species: Rt
Applications: ELISA
Monkey IL-10 ELISA Kit (Color ...
Monkey IL-10 ELISA Kit (Colorimetric)
Species: Mk
Applications: ELISA
IL-10 Overexpression Lysate
IL-10 Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human IL-10 Prote ...
Recombinant Human IL-10 Protein
Species: Hu
Applications: Bioactivity
Recombinant Mouse IL-10 Prote ...
Recombinant Mouse IL-10 Protein
Species: Mu
Applications: Bioactivity
Recombinant Human IL-10 Prote ...
Recombinant Human IL-10 Protein
Species: Hu
Applications: Func, PAGE, Bioactivity


Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Human IL10 is a non glycosylated polypeptide consisting of 178 amino acids. There is 73% homology between the human and mouse IL10 proteins, however, the human IL10 acts on both human and mouse target cells, while the mouse IL10 has species specific activity. The cellular sources of IL10 are CD4+ T cells and T cell clones, thymocytes, B cells and B cell lymphomas, macrophages, mast cell lines and keratinocytes. IL10 will stimulate the growth of stem cells, mast cells and thymocytes. IL10 enhances cytotoxic T cell development, and costimulates B cell differentiation and immunoglobulin secretion. IL10 inhibits cytokine production by macrophages and suppresses macrophage class II MHC expression. The human IL10 gene is on human chromosome 1.


Entrez Human
Uniprot Human
Product By Gene ID 3586
Alternate Names
  • TGIF
  • interleukin-10
  • IL10A
  • IL-10MGC126451
  • CSIFMGC126450
  • Cytokine synthesis inhibitory factor
  • interleukin 10

Research Areas for IL-10

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cytokine Research
Innate Immunity

Bioinformatics Tool for IL-10

Discover related pathways, diseases and genes to IL-10. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related IL-10 Blog Posts

Check out the latest blog posts on IL-10.
Success of combined IL-10 and IL-12 therapy in colon cancer depends on IFN-gamma and gut barrier integrity
By Jamshed Arslan, Pharm. D., PhD. Colon cancer is responsible for over 600,000 deaths per year worldwide. Colon cancer can be classified into two categories: mismatch repair (MMR)-deficient and MMR-proficient cancers...    Read more.
How to identify B cell subsets using flow cytometry
By Victoria OsinskiUsing flow cytometry to identify B cell subsetsIdentifying cellular subsets by flow cytometry requires careful and thorough planning in order to ensure the correct subset of cells are identified a...    Read more.
PPAR gamma - An important target in human metabolism
Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells by interacting with members of the nuclear hormone receptor superfamily known as peroxisome proliferator activated receptors (PPARs). There are f...    Read more.
CD11b: Marker for a New Type of B Cell that Participates in Cell-Mediated Immunity
Think B lymphocytes just produce antibodies? Think again! Although, of course, B cells are vital for the humoral immune response, many studies in recent years have begun to uncover antibody-independent actions of B cells: regulating T cells and thus a...    Read more.
Read more IL-10 related blogs.